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Volume 44 Issue 2
May  2021
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Article Navigation >  Journal of Molecular Imaging  > 2021  >  44(2): 341-345
Xueyan TIAN, Xiaoming YIN, Bin ZHANG. Value of DCE-MRI, DTI and their combination in the differential diagnosis of central prostate nodules[J]. Journal of Molecular Imaging, 2021, 44(2): 341-345. doi: 10.12122/j.issn.1674-4500.2021.02.25
Citation: Xueyan TIAN, Xiaoming YIN, Bin ZHANG. Value of DCE-MRI, DTI and their combination in the differential diagnosis of central prostate nodules[J]. Journal of Molecular Imaging, 2021, 44(2): 341-345. doi: 10.12122/j.issn.1674-4500.2021.02.25
shu

Value of DCE-MRI, DTI and their combination in the differential diagnosis of central prostate nodules

doi: 10.12122/j.issn.1674-4500.2021.02.25
  • 1.

    Department of Urological Surgical, Shengjing Hospital of China Medical University, Shenyang 110004, China

  • 2.

    Department of Medical imaging, Shengjing Hospital of China Medical University, Shenyang 110004, China

  • Received Date: 2021-03-04
  • Publish Date: 2021-03-20
    Abstract
  • ObjectiveTo investigate the value of dynamic contrast-enhanced MRI (DCE-MRI), diffusion tensor imaging (DTI) and their combination in the differential diagnosis of central prostate nodules.MethodsFrom January 2019 to June 2020, 79 patients with central prostate nodules in our hospital, 91 nodules, were examined by DCE-MRI and DTI, and the differences of parameters between benign and malignant nodules were analyzed.ResultsThe pathological diagnosis was made, among the 91 nodules; 39 were malignant and 52 were benign. The Tmax of DCE-MRI parameters of malignant nodules was 103.36 ± 32.50s, which was significantly lower than that of benign nodules (P < 0.05), while the enhancement rate and Ktrans were (4.90± 1.10)% and 12.20±4.11 min-1, which were significantly higher than those of benign nodules (P < 0.05). The proportion of TIC type Ⅲ in malignant nodules was 84.62%, which was significantly higher than that in benign nodules (P < 0.05). The proportion of TIC type Ⅱ in benign nodules was 80.77%, which was significantly higher than that in malignant nodules (P < 0.05). There was no significant difference in the proportion of TIC type Ⅰ between benign and malignant nodules (P>0.05). The ADC value of malignant nodules was (1.03±0.22)×10-3 mm2/s, which was significantly lower than that of benign nodules (P < 0.05), while the FA was 0.32 ± 0.10, which was significantly higher than that of benign nodules (P < 0.05). The area under ROC curve of Tmax, enhancement rate, Ktrans, TIC type, ADC, FA and combined diagnosis of central prostate malignant nodules were 0.870, 0.883, 0.868, 0.838, 0.903, 0.885 and 0.933, respectively (P < 0.05).ConclusionDCE-MRI, DTI and combined diagnosis have good application value in the differential diagnosis of central prostate nodules and is worthy of clinical use.

     

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