Brief Rs-fMRI analysis methods commonly used in clinical studies of acupuncture in recent 10 years

Xuan GAO; Hai LU; Xiaoying GAO; Chunhong ZHANG

doi:10.12122/j.issn.1674-4500.2020.04.03

Volume 43 Issue 4

Dec. 2020

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Xuan GAO, Hai LU, Xiaoying GAO, Chunhong ZHANG. Brief Rs-fMRI analysis methods commonly used in clinical studies of acupuncture in recent 10 years[J]. Journal of Molecular Imaging, 2020, 43(4): 568-571. doi: 10.12122/j.issn.1674-4500.2020.04.03

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Xuan GAO, Hai LU, Xiaoying GAO, Chunhong ZHANG. Brief Rs-fMRI analysis methods commonly used in clinical studies of acupuncture in recent 10 years[J]. Journal of Molecular Imaging, 2020, 43(4): 568-571. doi: 10.12122/j.issn.1674-4500.2020.04.03

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Brief Rs-fMRI analysis methods commonly used in clinical studies of acupuncture in recent 10 years

doi: 10.12122/j.issn.1674-4500.2020.04.03

Xuan GAO^{1,2
,},
Hai LU^1,2,
Xiaoying GAO^1,2,
Chunhong ZHANG^{1,2,3,4
,
,}

1.
Department of Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
2.
Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China
3.
Department of Acupuncture and Moxibustion, Baoan Pure Traditional Chinese Medicine Treatment Hospital, Shenzhen 518000, China
4.
National Clinical Medicine Research Center of Traditional Chinese Medicine, Tianjin 300381, China

Received Date: 2020-07-26
Publish Date: 2020-10-20

Abstract

Abstract

Rs- fMRI is a scientific method to explore brain activity in clinical acupuncture which assists researchers to draw research conclusions and provide feedback in clinical practice.There were three kinds of RS fMRI analysis methods commonly used in acupuncture clinical research in recent 10 years: Regional Homogeneity (ReHo), Amplitude Of Low Frequency Fluctuation (AlFF) and Functional Connectivity(FC). In acupuncture research, ReHo could be used to analyse the activation or inhibition of a acupoint in a certain or several brain regions, so as to acknowledge the target effect brain area of the acupoint, and lay a foundation for the study of "acupoint-brain-disease". ALFF could directly reflect the intensity of spontaneous synchrony of local neurons, and to a certain extent, reflect the interaction and neural network connections of relevant brain regions. FC obtained the functional connections between brain regions, namely the "highway" of brain regions, which was easy to understand and the results are direct. Different analysis methods showed the brain activity of acupuncture at different acupoints, such as the synchronization of local nerve activity, the connectivity between adjacent brain areas, the spontaneous fluctuation and functional activity of the brain.This paper elaborates the applicable research directions of ReHo, ALFF and FC analysis methods in acupuncture research.
- acupuncture,
- functional nuclear magnetic resonance,
- Rs-fMRI,
- regional homogeneity,
- amplitude of low frequency fluctuation,
- functional connectivity

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References(28)

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Brief Rs-fMRI analysis methods commonly used in clinical studies of acupuncture in recent 10 years

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