Clinical Effect of Tea Polyphenols and Tinidazole for Adjuvant therapy to chronic periodontitis
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摘要:
目的探讨茶多酚联合替硝唑含片治疗慢性牙周炎的临床效果。 方法选取医院于2013年9月~2015年4月收治的慢性牙周炎患者73例，对照组（38例）给予替硝唑含片进行治疗，观察组（35例）在对照组基础之上给予茶多酚联合治疗，并在两组患者结束治疗后，对比其治疗总有效率、菌斑指数、牙周探针深度、附着水平丧失、牙齿松动度及不良反应率。 结果两组患者经过治疗，观察组总有效率为91.4%与对照组的76.3%比较，差异没有统计学意义（P>0.05），观察组的治疗显效率为42.9%，对照组的治疗显效率为21.1%，差异有统计学意义（P<0.05）。观察组患者的菌斑指数、牙周探针深度、附着水平丧失、牙齿松动度均低于对照组（P<0.05），观察组不良反应率5.7%低于对照组患者21.1%，差异没有统计学意义（P>0.05）。 结论茶多酚联合替硝唑含片治疗慢性牙周炎能够有有显著的疗效，能有效抑制牙菌斑，值得在临床实践过程中应用和推广。 Abstract:ObjectiveTo investigate the Clinical Effect of Tea Polyphenols and Tinidazole Buccal for Adjuvant therapy to chronic periodontitis. MethodsA total of 73 patients with chronic periodontitis from Sep 2013 to April 2015 were divided into control group and observation group.38 cases in control group were treated with Tinidazole, and 33 cases in observation group were combined with Tea Polyphenols. The total efficacy, PLI, PD, AL, TM and occurrence of adverse reactions of two groups were compared. ResultsAfter treatment the total efficacy of observation group (91.4%) higher than that in control group (76.3%) with no significance (P>0.05). The excellent efficacy of observation group (42.9%) significantly higher than that in control group (21.1%) (P<0.05). The PLI, PD, AL, TM of observation group significantly lower than that in control group. The occurrence of adverse reactions of observation group (5.7% ) lower than that in control group (21.1% )with no significance(P>0.05). ConclusionsThe treatment of Tea Polyphenols and Tinidazole for Adjuvant therapy to chronic periodontitis has excellent efficacy and can inhibit the development of dental plaque, which is worthy to popularizing in clinical. -
Key words:
- tea polyphenols /
- tinidazole /
- chronic periodontitis
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表 1 两组患者临床疗效比较（例，%）
组别 n 显效 有效 无效 总有效率 对照组 38 8(21.1) 21(55.3) 9(23.7) 76.3 观察组 35 15(42.9) * 17(48.6) 3(8.6) 91.4 *P<0.05 vs 对照组. 
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表 2 两组患者牙周改善情况比较
组别 n 菌斑指数 牙周探针深度 附着水平丧失 牙齿松动度 对照组 38 1.8±0.4 4.2±0.6 4.4±0.7 1.1±0.6 观察组 35 1.6±0.4* 3.8±0.6* 3.9±0.6* 0.8±0.4* *P<0.05 vs 对照组.
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