Clinical significance of hemoglobin/platelet ratio in predicting the risks for patients with gastrointestinal bleeding
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摘要:
目的评价血红蛋白（Hb）与血小板（PLT）比值在预测急诊消化道出血（GIB）患者的灵敏度及特异度。 方法收集GIB患者103例，观察在院期间是否再次出现GIB（RGIB），比较其Hb、PLT及Hb/PLT三者在预测RGB的差异。 结果以上患者当中22例出现RGIB，发生率为21.4%。Hb与RGIB无显著相关性（P=0.682）；PLT及Hb/PLT与RGIB存在显著相关性（P=0.007，0.004）。PLT的曲线下面积（AUC）为0.160（95%CI: -0.058~0.378）；显著低于Hb/PLT的AUC值0.860（95%CI: 0.657~1.063）。当Hb/PLT比值为2.660时，其预测RGIB的敏感度为0.840，特异度为0.857。 结论Hb/PLT比值预测RGIB优于单纯Hb或PLT，且该比值的敏感度及特异度均高，有望成为防治急诊GIB患者的简化、实用性指标。 -
关键词:
- 消化道出血 /
- 血红蛋白/血小板比值 /
- 危险因素 /
- 敏感度 /
- 特异度
Abstract:Objective To evaluate the hemoglobin (Hb) and platelets (PLT) ratio in the prediction of emergency gastrointestinal bleeding (GIB) in patients with sensitivity and sensitivity. Methods 103 patients with collecting GIB, observe whether during the period of school once again GIB (RGIB), compare the Hb, PLT and Hb/PLT in predicting the RGB difference. Results The patients of 22 cases with RGIB, rate of 21.4%. Hb no significant correlation with RGIB (P=0.682); PLT and Hb/PLT and RGIB exist significant correlation (P=0.007, 0.007). PLT area under curve (AUC) was 0.160 (95% CI: 0.058~0.058); Significantly lower than that of Hb/PLT AUC value of 0.860 (95% CI: 0.657~0.657). When Hb/PLT ratio is 2.660, the predicted RGIB sensitivity of 0.840, 0.857. Conclusions Hb/PLT RGIB ratio prediction is better than that of pure Hb or PLT, and the sensitivity of this ratio and specific degree is high, is expected to be simplified and practical indicator of prevention and treatment of patients with emergency GIB. -
Key words:
- gastrointestinal bleeding /
- hemoglobin/platelet ratio /
- risk factors /
- sensitivity /
- specificity
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图 1 ROC曲线图
注: 横轴代表误诊率（1-特异度）, 纵轴代表敏感度; 最左侧的蓝色曲线为Hb/PLT比值, 中间的绿色曲线为Hb, 最右侧的黄色曲线为PLT; 紫色的对角线为诊断参考线.
表 1 两组GIB患者Hb、PLT及HB/PLT比值的比较
分组 n Hb(T/L) PLT (G/L) Hb/PLT RGIB 22 68.29±17.34 79.32±43.64 3.72±2.18 NGIB 81 87.61±24.17 103.27±54.35 1.06±0.51 t -7.678 -9.624 3.023 P 0.028 0.019 0.012 
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