Application of lauromacrogol in varicose veins
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摘要:
目的探讨聚桂醇在下肢静脉曲张中的应用效果。 方法选取我院于2013年9月~2015年9月共256例下肢静脉曲张患者,随机分为两组,各128例,对照组患者进行传统的大隐静脉高位结扎,观察组患者进行聚桂醇泡沫多点注射,比较两组患者的临床效果。 结果两种治疗方法的治疗总有效率均为100%,聚桂醇组患者的一期治愈率为90.63%(116例),二期治愈率为9.37%(12例);传统治疗组患者的一期治愈率为88.28%(113例),二期治愈率为10.16%(13例)。两组患者治疗后其症状的改善情况基本一致,但在手术时间、患者早期下床活动时间、治疗后患肢的美观程度、住院时间和治疗费用等指标上,聚桂醇组显著优于对照组。且聚桂醇组患者出现并发症的发生率和严重程度远低于传统治疗组(P<0.05)。 结论聚桂醇泡沫浅静脉多点注射治疗下肢静脉曲张,操作简单,且微创美观,安全性高,患者所经受的痛苦小,治疗依从性高,患者治疗后并发症发生率低。 Abstract:Objective To investigate the clinical efficacy of lauromacrogol for varicose veins. Methods During September 2013 to September 2015, 256 cases of patients with varicose veins were randomly divided into two groups. The control group were performed traditional saphenous vein ligation, and the observation group were performed multi-point injection with lauromacrogol foam. Results Total effective rate of two treatment methods ware 100%, cure rate of observation group in term 1 was 90.63% (116 cases), cure rate in term 2 was 9.37% (12 cases); the cure rate of traditional group in term 1 was 88.28% (113 cases), cure rate in term 2 was 10.16% (13 cases). Improvement of symptoms were basically the same after treatment, however, lauromacrogol group was significantly better than the control group in surgery length, ambulation time, limb aesthetic level, length of stay and costs. The incidence and severity of complications in lauromacrogol group were much lower than control group (P<0.05). Conclusion Multi-point injection with Lauromacrogol foam for varicose veins is simple, effective, minimally invasive and safe with less pain, high compliance and lower rate of complications. -
Key words:
- lauromacrogol /
- vein varicose /
- foam sclerotherapy
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表 1 两组患者临床资料比较(n=128)
组别 男性患者 女性患者 年龄范围(岁) 平均年龄(岁) 双侧 左侧 右侧 对照组 85 43 19~82 53.1 14 55 62 观察组 89 39 20~83 51.1 12 50 63 表 2 两组患者围手术期、治疗费用及患肢美观程度的比较(n=128)
组别 手术时间(min) 患者早期下床时间(d) 住院时间(d) 治疗费用(元) 美观程度满意率[n(%)] 对照组 54.0±7.5 3.0±2.5 5.5±2.5 2900.0±750.5 102(79.69%) 观察组 24.0±6.5 1.5±1.5 1.5±0.5 1450±55.5 122(95.31%) t=34.1986 t=5.8209 t=17.7504 t=21.7991 χ2=12.8929 P 0.0000 0.0000 0.0000 0.0000 0.0003 -
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