The clinical significance of the change of the pulse perfusion index in neonatal asphyxia
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摘要:
目的探讨新生儿窒息患儿脉搏灌注指数变化的临床意义。 方法选取2015年3~10月所在包钢三医院所出生的足月窒息新生儿96例（窒息组），并将其分为休克组及非休克组，并根据患儿具体病情给予患儿相应的窒息复苏及抗休克治疗；随机选取同一时期分娩的足月新生儿96例作为正常对照组，生后按时开奶，按需哺乳。分别记录所有纳入研究患儿出生后、24 h、72 h的脉搏灌注指数数值。 结果窒息组患儿出生时的PI值明显低于正常对照组新生儿；休克组患儿出生时及在给予治疗24 h后PI值明显低于非休克组，在给予患儿综合治疗72 h后休克组与非休克组两组PI值差异无统计学意义；休克组经综合治疗24 h后，PI值与出生时比较无统计学意义，休克组经治疗72 h后PI值较其出生时明显升高；非休克组患儿经过综合治疗24 h和72 h后，其PI值与出生时比较均无统计学意义。 结论窒息患儿的脉搏灌注指数的变化可以反应患儿的窒息及休克情况，脉搏灌注指数的恢复提示患儿病情的改善。 Abstract:Objective To investigate neonatal asphyxia pulse perfusion index change clinical significance. Methods A total of 96 cases of full-term newborn asphyxia (asphyxia group), and divided into shock group and non-shock group, and give neonates the appropriate resuscitation and anti-shock therapy according to the specific condition of neonate ; the same period were randomly selected birth 96 cases of full-term newborns as normal control group, open on time after raw milk, breastfeeding on demand. All included studies were recorded in neonates born after 24 hours and 72 hours of pulse perfusion index values. Results PI values in Neonates with birth asphyxia group were significantly lower than that in control group. Neonates with shock group after giving birth and 24 hours PI treatment was significantly lower than that in non-shock group, in the comprehensive treatment given to neonates after 72 hours shock group and non-shock group PI values of the two groups showed no significant difference; shock group after comprehensive treatment 24 h, no significant difference when the PI and birth, birth shock group was significantly higher than its value by PI after treatment 72 h; non-shock group of neonates through comprehensive treatment after 24 h and 72 h, which PI values were not statistically significant compared with at birth. Conclusion Pulse perfusion index changes can response asphyxia and shock situation of children, to improve the recovery prompt pulse perfusion index of children with the disease. -
Key words:
- pulse perfusion index /
- PI /
- newborns /
- asphyxia /
- shock
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表 1 休克组和非休克组PI值比较（x±s）
组别 n PI 值 出生时 治疗24 h 治疗72 h 非休克组 68 1.12±0.64 1.28±0.63 1.24±0.32 休克组 28 0.58±0.43* 0.64±0.59* 1.14±0.57* 
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