The correlation between serum-ascites total protein gradient and liver size parameters
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摘要:
目的探讨血清-腹水总蛋白梯度（SATPG）与肝脏超声参数的相关性。 方法666例肝硬化并腹水患者经彩色多普勒超声测定肝脏左肝上下径、左肝前后径、右肝厚度、右肝斜径、门静脉管径和门静脉血流速度；同时测定血清和腹水总蛋白浓度，二者差值为SATPG。分析SATPG与肝脏超声参数的关系。 结果SATPG与谷草转氨酶、谷丙转氨酶、白蛋白、球蛋白以及总胆红素均存在明显相关（P<0.05）；SATPG与右肝斜径、左肝前后径不存在相关性（P>0.05）；SATPG与左肝上下径、右肝厚度、门静脉管径和门静脉血流速度存在明显相关（P<0.05）。 结论SATPG可以反映肝硬化腹水患者肝硬化程度和门静脉高压，同时也可以反映了患者肝功能情况。 Abstract:Objective To investigate the correlation between serum-ascites total protein grdient (SATPG) and liver size. MethodsA total of 666 patients with ascites were examined with color doppler ultrasonography. SATPG was examined with abdominalparacentesis, which was the difference of total protein between serum and ascites. Pearson correlation analysis was used toassess the correlation between SATPG and the up-down length of left lobe of liver, the front-back length of left lobe of liver, thethickness of right lobe of liver, portal vein diameter, and portal vein blood flow velocity. Results There were no correlationsbetween the levels of SATPG and oblique diameter of right liver , the front-back length of left lobe of liver (r=-0.034, P=0.387; r=?0.048, P=0.219). However, the correlation coefficients between the levels of SATPG and the up-down length of left lobe of liver,the thickness of right lobe of liver, portal vein diameter, and portal vein blood flow velocity were -0.089, -0.082, 0.107and -0.131, respectively (P<0.05). Conclusion SATPG can be a good index to reflect the degree of portal pressure, liver size andliver function． -
Key words:
- serum /
- ascties /
- total protein /
- liver cirrhosis /
- portal hypertension
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表 1 血清-腹水总蛋白梯度（SATPG）与患者肝功能和肝脏超声参数的关系
临床参数 SATPG r P ALT（U/L） 69.60±85.06 0.101 0.009 AST（U/L） 129.96±143.66 0.095 0.015 ALB（g/L） 31.64±4.98 -0.167 0.000 GLB（g/L） 31.74±7.97 0.571 0.000 TBIL（μmol/L） 207.70±240.15 0.086 0.027 左肝上下径（mm） 62.92±18.87 -0.089 0.022 左肝前后径（mm） 62.62±11.57 -0.048 0.219 右肝厚度（mm） 95.15±12.28 -0.082 0.035 右肝斜径（mm） 31.90±8.92 -0.034 0.387 门静脉管径（mm） 12.41±2.17 0.107 0.006 门径血流速度（cm/s） 19.30±5.03 -0.131 0.001 
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