Preliminary application of magnetic resonance dynamic scanning for evaluating swallowing function in NPC patients without pharyngeal symptoms after radiotherapy
-
摘要:
目的探讨磁共振Fast GRE+Asset序列动态扫描在鼻咽癌（NPC）患者放疗后无自觉症状吞咽功能评价的初步应用。 方法对80例放疗后NPC患者训练其掌握吞咽要领，在GE 3.0T磁共振系统上选用fast GRE序列，并结合Asset技术（加速因子均为2.0ph），对咽部进行吞咽过程的单层矢状位动态快速扫描，分别连续采集60幅图像，并自动生成动态电影图像，采用双盲法对所获得的全部图像分别进行目测评价。 结果80例患者全部成功完成检查，咽部形态显示清晰，会厌、软腭、舌部、肌肉清晰显示率分别为92.5%、98.75%、93.75%、95%。动态电影图像能清楚显示整个吞咽过程，完整展示吞咽动作过程中会厌、软腭、舌部，以及参与吞咽过程有关肌肉的变化过程。 结论用fast GRE+Asset序列做吞咽动态矢状位磁共振成像，可以较好地评价NPC患者放疗后的吞咽功能。 Abstract:ObjectiveTo investigate the preliminary application of fast magnetic resonance GRE + Asset sequence dynamic scanning for evaluating swallowing function in nasopharyngeal carcinoma (NPC) patients without pharyngeal symptoms after radiotherapy. Methods80 cases were trained to master the essentials of swallowing, and the fast GRE sequence combined with the Asset technology (acceleration factor are 2.0ph) were sued to perform a single sagittal slice fast dynamic scanning on GE 3.0T MRI system. 60 continuous images of pharyngeal in the slow swallowing state were obtained on each pertain. Dynamic cine images were generated automaticly. All the images were visually evaluated with double blind method. ResultsSuccessful examinations were completed on all of the 80 patients. The pharyngeal morphology were displayed clearly. The clear display rate of the epiglottis, soft palate, tongue and muscles were 92.5%, 98.75%, 93.75%, 95%, respectively. A whole swallowing process of the pharyngeal could be observed clearly on the dynamic cine images, and related changes of the epiglottis, soft palate, tongue, and muscles, which participated the swallowing process, were also displayed perfectly during the swallowing action. ConclusionsThe fast GRE + Asset sequence could be used to evaluate the swallowing function in patients with NPC after radiotherapy. -
[1] 张婧, 艾林, 陈鸿雁, 等.正常成人皮质吞咽中枢功能磁共振的初步研究[J].中国卒中, 2006, 1(4): 481-3. http://www.cnki.com.cn/Article/CJFDTOTAL-ZUZH200607007.htm [2] Barkhausen J, Goyen M, Von Winterfeld F, et al. Visualization of swallowing using real-time TrueFISP Mr fluoroscopy[J]. Eur Radiol, 2002, 12(1): 129-33. doi: 10.1007/s00330-001-1146-8 [3] 于帆, 兰月, 窦祖林, 等.空吞咽与食团吞咽对健康人咽期吞咽功能的影响[J].中国康复医学杂志, 2014, 29(3): 218-22. http://www.cnki.com.cn/Article/CJFDTOTAL-ZGKF201403006.htm [4] 杨镜全, 高明勇, 罗素玲, 等.吞咽过程动态MRI的可行性探讨[J].国际放射医学核医学杂志, 2012, 36(1): 52-5. http://d.wanfangdata.com.cn/Periodical_gwyx-fsyxhyxfc201201013.aspx [5] 邱建峰, 王飞跃, 王晓燕, 等.核磁共振成像质量控制的信噪比分析[J].泰山医学院学报, 2008, 29(1): 32-5. http://www.cnki.com.cn/Article/CJFDTOTAL-TSYX200801013.htm [6] Nasreddin DAbolmaali, Jan Schmitt W, Schwarz DE. Toll Visualization of the articular disk of the temporomandibular joint in near-real-time MRI: feasibility study[J]. Eur Radiol, 2004, 14: 1889-94. https://www.researchgate.net/publication/8337155_Visualization_of_the_articular_disk_of_the_temporomandibular_joint_in_near-real-time_MRI_Feasibility_study [7] 吴军发, 胡永善, 吴毅, 等.健康成人吞咽口腔期的功能磁共振成像研究[J].中国康复医学杂志, 2013, 28(9): 789-93. http://www.cnki.com.cn/Article/CJFDTOTAL-ZGKF201309002.htm [8] 宋承汝, 程敬亮, 孙梦恬, 等.鼻咽部淋巴瘤的MR平扫及动态增强特征[J].中国医学影像技术, 2013, 29(10): 1611-5. http://www.cnki.com.cn/Article/CJFDTOTAL-ZYXX201310015.htm [9] 周惠嫦, 张盘德.吞咽训练配合针灸治疗鼻咽癌放疗后吞咽障碍[J].中国康复理论与实践, 2006, 12(1): 58-9. http://www.cnki.com.cn/Article/CJFDTOTAL-ZKLS200601027.htm [10] 张婧, 魏娜, 张亚清, 等.卒中后吞咽延迟患者与健康志愿者吞咽任务相关功能磁共振的对比研究[J].中国卒中杂志, 2007, 2(3): 209-13. http://www.cnki.com.cn/Article/CJFDTOTAL-ZUZH200703008.htm -
下载:
点击查看大图
图(1)
计量
- 文章访问数: 617
- HTML全文浏览量: 227
- PDF下载量: 2
- 被引次数: 0
