扩散张量成像独特神经显像优势在临床中的应用价值与进展

朱晓云; 沈龙山; 邹文涛

doi:10.12122/j.issn.1674-4500.2023.06.33

扩散张量成像独特神经显像优势在临床中的应用价值与进展

doi: 10.12122/j.issn.1674-4500.2023.06.33

朱晓云^{1, 3,},
沈龙山^{1, 3, 4, ,},
邹文涛^{2, 3}

1.
蚌埠医学院第二附属医院放射科，安徽蚌埠 233040
2.
蚌埠医学院第一附属医院放射科，安徽蚌埠 233099
3.
蚌埠医学院医学影像学院，安徽蚌埠 233030
4.
数字医学与智慧健康安徽普通高校重点实验室（蚌埠医学院），蚌埠医学院临床应用解剖研究所，安徽蚌埠 233004

基金项目:

蚌埠医学院转化医学重点项目 BYTM2019045

儿童语言发展模式与语言中枢结构网络发育关联性研究 AHCM2022Z006

详细信息

作者简介:
朱晓云，在读硕士研究生，住院医师，E-mail: 1425397929@qq.com

通讯作者:
沈龙山，硕士生导师，主任医师，E-mail: trede@163.com

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出版历程
- 收稿日期: 2023-08-01
- 网络出版日期: 2023-12-26
- 刊出日期: 2023-11-20

Application value and progress of diffusion tensor imaging's unique neuroimaging advantages in clinical practice

ZHU Xiaoyun^{1, 3
,},
SHEN Longshan^{1, 3, 4
, ,},
ZOU Wentao^{2, 3}

1.
Department of Radiology, Second Affiliated Hospital of Bengbu Medical College, Bengbu 233040, China
2.
Department of Radiology, First Affiliated Hospital of Bengbu Medical College, Bengbu 233099, China
3.
School of Medical Imaging, Bengbu Medical College, Bengbu 233030, China
4.
Key Laboratory of Digital Medicine and Intelligent Health in Anhui Universities (Bengbu Medical College), Institute of Clinical Applied Anatomy, Bengbu Medical College, Bengbu 233004, China

摘要

摘要: 磁共振成像技术在显示脑组织结构、判断颅内病变方面具有独特优势。随着成像技术的不断发展，出现了许多功能磁共振成像新技术。扩散张量成像是在弥散加权成像序列的基础上发展出的新序列，扩散张量成像根据脑组织中水分子的扩散内在方向性，能够完整的显示出神经纤维束走形，是目前唯一能在活体内评估神经纤维束微观结构的无创性成像方法。神经细胞是永久细胞，不具有再生能力，脑组织发生病变后的常见后遗症（如中枢性偏瘫、意识障碍、感觉障碍），多是由于病变部位神经细胞缺血受损，颅内神经纤维联系传导中断所导致。通过扩散张量成像早期对病灶区域的神经受损程度进行评估，有利于临床确定更精准的诊疗方案，进而早期干预、改善预后。利用其独特神经显像优势，本文主要围绕可导致神经细胞变性的疾病（如脑卒中、脑肿瘤、神经系统退行性疾病、癫痫及脑发育障碍等），通过扩散张量成像在辅助早期诊断、协助临床治疗及预测患者远期预后等几个方面的应用，探讨其在临床中的应用价值与进展。
- 扩散张量成像 /
- 神经系统疾病 /
- 应用价值
Abstract: Magnetic resonance imaging technology has unique advantages in displaying brain tissue structure and identifying intracranial lesions. With the continuous development of imaging technology, many new functional magnetic resonance imaging technologies have emerged. Diffusion tensor imaging is a new sequence developed on the basis of diffusion weighted imaging sequence. Based on the intrinsic directionality of water molecules diffusion in brain tissue, diffusion tensor imaging can fully display the shape of nerve fiber bundles, and is currently the only non-invasive imaging method that can evaluate the microstructure of nerve fiber bundles in vivo. Neural cells are permanent cells that do not have the ability to regenerate. Common sequelae after brain tissue lesions (such as central hemiplegia, consciousness disorders, sensory disorders) are often caused by ischemic damage to nerve cells at the lesion site and interruption of intracranial nerve fiber transmission. Early assessment of the degree of nerve damage in the lesion area through diffusion tensor imaging is beneficial for clinical determination of more accurate diagnosis and treatment plans, which can lead to early intervention and improved prognosis. This article mainly focuses on diseases that can cause neurodegeneration (such as stroke, brain tumors, degenerative diseases of the nervous system, epilepsy, and developmental disorders of the brain), explore the clinical application value and progress of diffusion tensor imaging in assisting early diagnosis, assisting clinical treatment, and predicting long- term prognosis of patients.
- diffusion tensor imaging /
- diseases of the nervous system /
- application value

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参考文献(53)

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扩散张量成像独特神经显像优势在临床中的应用价值与进展

doi: 10.12122/j.issn.1674-4500.2023.06.33

作者简介:
朱晓云，在读硕士研究生，住院医师，E-mail: 1425397929@qq.com

通讯作者:
沈龙山，硕士生导师，主任医师，E-mail: trede@163.com

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Application value and progress of diffusion tensor imaging's unique neuroimaging advantages in clinical practice

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目录

留言板

扩散张量成像独特神经显像优势在临床中的应用价值与进展

doi: 10.12122/j.issn.1674-4500.2023.06.33

作者简介: 朱晓云，在读硕士研究生，住院医师，E-mail: 1425397929@qq.com

通讯作者: 沈龙山，硕士生导师，主任医师，E-mail: trede@163.com

计量

出版历程

Application value and progress of diffusion tensor imaging's unique neuroimaging advantages in clinical practice

计量

出版历程

目录

作者简介:
朱晓云，在读硕士研究生，住院医师，E-mail: 1425397929@qq.com

通讯作者:
沈龙山，硕士生导师，主任医师，E-mail: trede@163.com