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正电子发射断层扫描存活心肌评估的图像分析与解读及其进展

吕玉虎 兰晓莉 覃春霞

吕玉虎, 兰晓莉, 覃春霞. 正电子发射断层扫描存活心肌评估的图像分析与解读及其进展[J]. 分子影像学杂志, 2023, 46(6): 1127-1132. doi: 10.12122/j.issn.1674-4500.2023.06.30
引用本文: 吕玉虎, 兰晓莉, 覃春霞. 正电子发射断层扫描存活心肌评估的图像分析与解读及其进展[J]. 分子影像学杂志, 2023, 46(6): 1127-1132. doi: 10.12122/j.issn.1674-4500.2023.06.30
LÜ Yuhu, LAN Xiaoli, QIN Chunxia. Image analysis and interpretation of positron-emission tomography myocardial viability assessment and its progress[J]. Journal of Molecular Imaging, 2023, 46(6): 1127-1132. doi: 10.12122/j.issn.1674-4500.2023.06.30
Citation: LÜ Yuhu, LAN Xiaoli, QIN Chunxia. Image analysis and interpretation of positron-emission tomography myocardial viability assessment and its progress[J]. Journal of Molecular Imaging, 2023, 46(6): 1127-1132. doi: 10.12122/j.issn.1674-4500.2023.06.30

正电子发射断层扫描存活心肌评估的图像分析与解读及其进展

doi: 10.12122/j.issn.1674-4500.2023.06.30
基金项目: 

国家自然科学基金 81873906

国家自然科学基金 82171985

详细信息
    作者简介:

    吕玉虎,在读硕士研究生,E-mail: yuhu980412@163.com

    通讯作者:

    覃春霞,博士,主任医师,E-mail: qin_chunxia@hust.edu.cn

Image analysis and interpretation of positron-emission tomography myocardial viability assessment and its progress

Funds: 

National Natural Science Foundation of China 81873906

National Natural Science Foundation of China 82171985

  • 摘要: 心血管疾病是造成全球死亡和疾病负担的主要原因之一。准确评价心肌活性不仅有助于心血管疾病患者的临床决策,对其预后也具有重要的价值。正电子发射断层扫描(PET)图像质量好,在诊断和评估已知或疑似冠状动脉疾病患者中准确性较高。经典的PET心肌血流灌注-葡萄糖代谢显像评估存活心肌的价值已得到公认。目前PET存活心肌评估的图像分析主要依靠视觉评估或半定量评价。近年来,随着各种图像软件自动分析的推广应用,更多定量指标的纳入为临床提供了更有价值的参考信息。软件和技术设备的持续进步也推动着PET在评估存活心肌中更好地发挥其优势,人工智能技术的兴起及一体化PET/MR的探索应用更为PET心肌活性成像与图像解读提供了新的手段,但新技术同样伴随着机遇与挑战。本文就PET存活心肌评估中常用的软件、图像显示、不同图像分析方法及相关进展进行综述。

     

  • 表  1  目前常见心脏PET图像分析软件及基本信息

    Table  1.   Cardiac PET image analysis software and basic information

    No. Name Team Image processing and analysis Quantitative perfusion Quantitative viability Quantitative gated Websites
    1 Corridor4DM INVIA Medical Imaging Solutions, America Fully automated, allowing users to adjust https://www.inviasolutions.com
    2 ECToolbox Emory University, America Fully automated, allowing users to adjust https://syntermed.com
    3 PMOD PMOD Technologies, Switzerland Fully automated, allowing users to adjust https://www.pmod.com
    4 QPET Cedars-Sinai Medical Center, America Fully automated, allowing users to adjust https://csaim.com
    下载: 导出CSV

    表  2  半定量5分法评分标准

    Table  2.   The standard of semi-quantitative 5-point scoring

    Score The degree of tracer uptake Percentage of tracer uptake
    0 Normal ≥70%
    1 Mildly reduced ≥50% and < 70%
    2 Moderately reduced ≥30% and < 50%
    3 Severely reduced ≥10% and < 30%
    4 Completely reduced < 10% or no uptake
    下载: 导出CSV

    表  3  不同图像分析与解读方法优点与不足

    Table  3.   The advantages and disadvantages of different methods for image analysis and interpretation

    Methods Advantages Disadvantages
    Visual assessment Convenient; Intuitive Subject to the subjective factors and experience of the observer; Low sensitivity and repeatability; Long calculation time
    Semi-quantitative Scoring Relatively simple and high repeatability; Parameters can be provided for clinical evaluation; Reduce the interference of subjective factors; Easy to misclassify scoring results; Lack of specificity due to relative quantification
    Software analysis High sensitivity and good repeatability; Quantitative indicators with objectivity; Shorten diagnostic time and improve efficiency; Rich functionality with new features in development Increased equipment cost; Lack of consistent protocols and specifications among software; Analysis results depend on software processing capabilities
    下载: 导出CSV
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出版历程
  • 收稿日期:  2023-07-28
  • 网络出版日期:  2023-12-26
  • 刊出日期:  2023-11-20

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