Advances in brain effects of laser acupuncture research in the last 20 years
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摘要: 激光针灸作为社会科技进步的时代产物,是一种将低水平激光应用于经络系统的治疗方法,拓宽了传统针灸技术的应用及发展,其脑效应研究于近20年兴起,本文从当前应用较多的功能磁共振成像、脑电图和经颅多普勒超声3种技术层面对激光针灸脑效应的研究进展及未来展望加以论述。研究表明激光针灸在刺激不同穴位时产生的脑效应能够体现穴位的特异性且与其主治存在关联,同时有相似作用的穴位产生的脑效应存在一定的相关性。目前激光针灸作用机制仍未探查清楚,脑效应研究为探索其治疗以疼痛为代表的某些疾病的疗效机制提供了新的视角,虽然仍面临着许多挑战,但未来有着广阔的发展前景。Abstract: As a product of social technological progress, laser acupuncture is a treatment that applies low-level laser therapy to the meridian system, which broadens the application and development of traditional acupuncture and moxibution, and the research of its brain effect has risen up in the past 20 years. The author consulted relevant literature and discussed the research progress and future prospects of brain effects on laser acupuncture at the level of three techniques, namely functional magnetic resonance imaging, electroencephalogram and multidirectional transcranial doppler-sonography that are being used currently. It is shown that the brain effects produced by laser acupuncture when stimulating different acupuncture points can reflect the specificity of the acupuncture points and correlate with their main treatment, while there is a correlation between the brain effects produced by acupuncture points with similar effects. At present, the research on the brain effects of laser acupuncture provide a new perspective for exploring the efficacy in the treatment of certain diseases represented by pain as it is still unexplored. Although there could be many challenges, it has a promising future.
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[1] Chon TY, Mallory MJ, Yang J, et al. Laser acupuncture: a concise review[J]. MedAcupunct, 2019, 31(3): 164-8. http://www.researchgate.net/publication/333636506_Laser_Acupuncture_A_Concise_Review [2] Litscher G. Definition of laser acupuncture and all kinds of photo acupuncture[J]. Medicines, 2018, 5(4): 117. doi: 10.3390/medicines5040117 [3] Mester E, Szende B, Spiry F, et al. Effects of the laser in wound healing[J]. Lyon Chir, 1971, 67(6): 416-9. [4] Law D, McDonough S, Bleakley C, et al. Laser acupuncture for treating musculoskeletal pain: a systematic review with meta-analysis [J]. JAcupunct Meridian Stud, 2015, 8(1): 2-16. doi: 10.1016/j.jams.2014.06.015 [5] Chen Z, Ma C, Xu L, et al. Laser acupuncture for patients with knee osteoarthritis: a systematic review and meta-analysis of randomized placebo-controlled trials[J]. Evid Based Complement Alternat Med, 2019, 2019: 6703828. http://www.ncbi.nlm.nih.gov/pubmed/31781275 [6] Glazov G, Yelland M, Emery J. Low-level laser therapy for chronic non- specific low back pain: a meta- analysis of randomised controlled trials[J]. Acupunct Med, 2016, 34(5): 328-41. doi: 10.1136/acupmed-2015-011036 [7] 李媛, 吴凡, 程珂, 等. 激光针灸镇痛效应机制研究进展[J]. 中华中医药杂志, 2018, 33(5): 2125-31. https://www.cnki.com.cn/Article/CJFDTOTAL-BXYY201805097.htm [8] Huang W, Pach D, Napadow V, et al. Characterizing acupuncture stimuli using brain imaging with FMRI: a systematic review and meta-analysis of the literature[J]. PLoS One, 2012, 7(4): e32960. doi: 10.1371/journal.pone.0032960 [9] Siedentopf CM, Golaszewski SM, Mottaghy FM, et al. Functional magnetic resonance imaging detects activation of the visual association cortex during laser acupuncture of the foot in humans[J]. Neurosci Lett, 2002, 327(1): 53-6. doi: 10.1016/S0304-3940(02)00383-X [10] 谢长倭, 吴季华, 谢昭贤, 等. 以功能性核磁共振造影初探10Hz调制激光针灸刺激所引发人类大脑皮质的活化现象[J]. 波谱学杂志, 2010, 27(3): 369-78. doi: 10.3969/j.issn.1000-4556.2010.03.008 [11] Hsieh CW, Wu JH, Hsieh CH, et al. Different brain network activations induced by modulation and nonmodulation laser acupuncture[J]. Evid Based Complementary Altern Med, 2011, 2011: 1-8. http://search.ebscohost.com/login.aspx?direct=true&db=aph&AN=82075240&site=ehost-live [12] Quah-Smith I, Williams MA, Lundeberg T, et al. Differential brain effects of laser and needle acupuncture at LR8 using functional MRI [J]. Acupunct Med, 2013, 31(3): 282-9. doi: 10.1136/acupmed-2012-010297 [13] Siedentopf CM, Koppelstaetter F, Haala IA, et al. Laser acupuncture induced specific cerebral cortical and subcortical activations in humans[J]. Lasers Med Sci, 2005, 20(2): 68-73. doi: 10.1007/s10103-005-0340-3 [14] Quah-Smith I, Sachdev PS, Wen W, et al. The brain effects of laser acupuncture in healthy individuals: an FMRI investigation[J]. PLoS One, 2010, 5(9): e12619. doi: 10.1371/journal.pone.0012619 [15] Quah-Smith I, Suo C, Williams MA, et al. The antidepressant effect of laser acupuncture: a comparison of the resting brain's default mode network in healthy and depressed subjects during functional magnetic resonance imaging[J]. MedAcupunct, 2013, 25(2): 124-33. [16] Lv J, Shi C, Deng Y, et al. The brain effects of laser acupuncture at thirteen ghost acupoints in healthy individuals: a resting- state functional MRI investigation[J]. Comput Med Imaging Graph, 2016, 54: 48-54. doi: 10.1016/j.compmedimag.2016.08.003 [17] Cohen MX. Where does EEG come from and what does it mean?[J]. Trends Neurosci, 2017, 40(4): 208-18. doi: 10.1016/j.tins.2017.02.004 [18] 张旭龙, 王明威, 白秀, 等. 基于EEG技术探讨针刺效应中枢机制的应用研究[J]. 针灸临床杂志, 2021, 37(8): 81-5. https://www.cnki.com.cn/Article/CJFDTOTAL-ZJLC202108017.htm [19] Litscher G, Bauernfeind G, Mueller-Putz G, et al. Laser-induced evoked potentials in the brain after nonperceptible optical stimulation at the Neiguan acupoint: a preliminary report[J]. Evid Based ComplementAlternat Med, 2012, 2012: 292475. http://www.biomedsearch.com/attachments/00/22/57/06/22570671/ECAM2012-292475.pdf [20] Knyazkova AI, Shulmina PV, Kistenev YV, et al. Influence of laser acupuncture on EEG characteristics[C]//Proc SPIE 11322, XIV International Conference on Pulsed Lasers and Laser Applications, 2019, 1132: 564-8. [21] Wu JH, Chang WD, Hsieh CW, et al. Effect of low- level laser stimulation on EEG[J]. Evid Based Complement Alternat Med, 2012, 2012: 951272. [22] Litscher G. Effects of acupressure, manual acupuncture and Laserneedle acupuncture on EEG bispectral index and spectral edge frequency in healthy volunteers[J]. Eur J Anaesthesiol, 2004, 21(1): 13-9. doi: 10.1097/00003643-200401000-00003 [23] Litscher G, Wang L, Wiesner-Zechmeister M. Specific effects of laserpuncture on the cerebral circulation[J]. Lasers Med Sci, 2000, 15 (1): 57-62. doi: 10.1007/s101030050048 [24] Knyazkova A, Shulmina P, Samarinova A, et al. Electroencephalography registration of laser acupuncture action on children with autism disorder[C]//Proceedings of the 13th International Joint Conference on Biomedical Engineering Systems and Technologies. February 24-26, 2020. Valletta, Malta. SCITEPRESS - Science and Technology Publications, 2020: 387-394. [25] 王晓冰, 李兴强, 高连波. 卒中的TCD相关进展[J]. 中国继续医学教育, 2020, 12(8): 83-6. doi: 10.3969/j.issn.1674-9308.2020.08.032 [26] Litscher G, Rachbauer D, Ropele S, et al. Acupuncture using laser needles modulates brain function: first evidence from functional transcranial Doppler sonography and functional magnetic resonance imaging[J]. Lasers Med Sci, 2004, 19(1): 6-11. http://www.ncbi.nlm.nih.gov/pubmed/15316852 [27] Litscher G, Schikora D. Cerebral vascular effects of non-invasive laserneedles measured by transorbital and transtemporal Doppler sonography[J]. Lasers Med Sci, 2002, 17(4): 289-95. doi: 10.1007/s101030200042 [28] Litscher G. Cerebral and peripheral effects of laserneedle®-stimulation[J]. Neurol Res, 2003, 25(7): 722-8. doi: 10.1179/016164103101202237 [29] Litscher G, Huang T, Wang L, et al. Violet laser acupuncture: part 1: Effects on brain circulation[J]. J Acupunct Meridian Stud, 2010, 3 (4): 255-9. doi: 10.1016/S2005-2901(10)60045-3 [30] Raith W, Pichler G, Sapetschnig I, et al. Near-infrared spectroscopy for objectifying cerebral effects of laser acupuncture in term and preterm neonates[J]. Evid Based Complement Alternat Med, 2013, 2013: 346852. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3671269/pdf/ECAM2013-346852.pdf [31] Litscher G. History of laser acupuncture: a narrative review of scientific literature[J]. MedAcupunct, 2020, 32(4): 201-8. http://www.researchgate.net/publication/343498464_History_of_Laser_Acupuncture_A_Narrative_Review_of_Scientific_Literature [32] Whittaker P. Laser acupuncture: past, present, and future[J]. Lasers Med Sci, 2004, 19(2): 69-80. doi: 10.1007/s10103-004-0296-8 [33] Lehrer J. Neuroscience: Making connections[J]. Nature, 2009, 457 (7229): 524-7. doi: 10.1038/457524a [34] 李香淑, 鲁海, 胡佳慧, 等. 基于多模态分子影像技术探讨针刺治疗中风病的脑证据群分析[J]. 时珍国医国药, 2021, 32(2): 487-9. doi: 10.3969/j.issn.1008-0805.2021.02.70 [35] 张元, 李香淑, 鲁海, 等. 基于fMRI技术探讨针刺治疗脑卒中阴阳经选穴脑效应差异[J/OL]. 中华中医药学刊, 2021. https://kns.cnki.net/kcms/detail/21.1546.R.20210910.1450.004.html. [36] 朱伟玲, 赵燕平, 郭邦红, 等. 激光针灸的作用机制与光源的选择依据[J]. 中国医药指南, 2012, 10(34): 598-600. doi: 10.3969/j.issn.1671-8194.2012.34.465 [37] Chow RT, David MA, Armati PJ. 830 nm laser irradiation induces varicosity formation, reduces mitochondrial membrane potential and blocks fast axonal flow in small and medium diameter rat dorsal root ganglion neurons: implications for the analgesic effects of 830 nm laser[J]. J Peripher Nerv Syst, 2007, 12(1): 28-39. doi: 10.1111/j.1529-8027.2007.00114.x [38] 秦茵, 钱兴皋, 刘奥, 等. 不同功率的低强度激光对神经病理性疼痛大鼠痛阈及脊髓背角5-HT、GABA表达的影响[J]. 颈腰痛杂志, 2016, 37(1): 23-7. https://www.cnki.com.cn/Article/CJFDTOTAL-JYTZ201601007.htm [39] Wattanathorn J, Sutalangka C. Laser acupuncture at HT7 acupoint improves cognitive deficit, neuronal loss, oxidative stress, and functions of cholinergic and dopaminergic systems in animal model of Parkinson's disease[J]. Evid Based Complement Alternat Med, 2014, 2014: 937601. http://www.ncbi.nlm.nih.gov/pubmed/25161693 [40] Khongrum J, Wattanathorn J. Laser acupuncture improves behavioral disorders and brain oxidative stress status in the valproic acid rat model of autism[J]. JAcupunct Meridian Stud, 2015, 8(4): 183-91. doi: 10.1016/j.jams.2015.06.008 [41] Jittiwat J. Laser acupuncture at GV20 improves brain damage and oxidative stress in animal model of focal ischemic stroke[J]. J Acupunct Meridian Stud, 2017, 10(5): 324-30. doi: 10.1016/j.jams.2017.08.003 [42] 卢咏琳. 激光针灸与传统针剌治疗脑性瘫痪儿童的临床研究[D]. 广州中医药大学, 2015. [43] 冯少玲, 李文纯. 激光针灸治疗原发性失眠疗效观察[J]. 山东中医杂志, 2018, 37(6): 494-6. https://www.cnki.com.cn/Article/CJFDTOTAL-SDZY201806017.htm [44] Velangi CS, Yavagal PC, Nagesh L. Role of auricular laser acupuncture and psychological counseling in reducing nicotine dependence due to smoking: A randomized controlled trial[J]. Indian J Public Health, 2021, 65(3): 243-9. [45] Yavagal PC, L N. Efficacy of Laser Auricular Acupuncture for Smoking Cessation: a randomised controlled trial[J]. Sultan Qaboos Univ Med J, 2021, 21(2): e275-81. doi: 10.18295/squmj.2021.21.02.017 [46] Putri DE, Srilestari A, Abdurrohim K, et al. The effect of laser acupuncture on spasticity in children with spastic cerebral palsy[J]. J Acupunct Meridian Stud, 2020, 13(5): 152-6. doi: 10.1016/j.jams.2020.09.001 [47] Yang Y, Litscher G, Sun ZR, et al. The application of laser acupuncture in animal experiments: a narrative review of biological aspects[J]. Evid Based ComplementaryAltern Med, 2021, 2021: 6646237. http://www.researchgate.net/publication/349598887_The_Application_of_Laser_Acupuncture_in_Animal_Experiments_A_Narrative_Review_of_Biological_Aspects/download [48] Moskvin SV, Agasarov LG. Laser acupuncture: 35 years of successful application in Russia (narrative review)[J]. J Lasers Med Sci, 2020, 11(4): 381-9. doi: 10.34172/jlms.2020.61
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