Application progress of diffusion tensor imaging in post-stroke depression
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摘要: 脑卒中是严重危害人民群众生命安全的疾病,位居我国致残率和致死率病因的首位,卒中后抑郁(PSD)是脑卒中后最为常见的大脑功能失调状态,其加剧卒中后的认知功能障碍,延缓卒中后的康复进程,增加卒中的致残率、病死率与复发率。弥散张量成像技术可以显示活体脑白质结构,被广泛应用于脑疾病的发病机制研究,并逐渐成为疗效评价的指标。本文综述了弥散张量成像技术在卒中后抑郁疾病中的应用情况,主要从卒中后抑郁的危险因素、发病机制假说、生物标记物方面进行概括分析,并阐述了基于弥散张量成像研究的卒中后抑郁的风险因素,旨在探讨其研究现状与应用进展。Abstract: Stroke is a serious disease endangering people's life and safety, ranking first in the cause of disability and mortality in China. Post-stroke depression is the most common brain dysfunction after stroke, which aggravates the cognitive dysfunction after stroke, delays the rehabilitation process after stroke, and increases the disability, mortality and recurrence rate of stroke. Diffusion tensor imaging, which can display the structure of white matter in vivo, has been widely used in the study of the pathogenesis of brain diseases, and has gradually become an indicator of curative effect evaluation. This paper reviews the application of diffusion tensor imaging in post-stroke depression, in order to explore its research status and application progress.
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Key words:
- post-stroke depression /
- diffusion tensor imaging /
- risk factor
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