功能磁共振成像技术在针刺治疗中风偏瘫脑机制研究的现状及前景

胡赫其; 鲁海; 韩李莎; 胡佳慧; 张春红

doi:10.12122/j.issn.1674-4500.2021.02.35

功能磁共振成像技术在针刺治疗中风偏瘫脑机制研究的现状及前景

doi: 10.12122/j.issn.1674-4500.2021.02.35

胡赫其^1,2,,
鲁海^1,2,
韩李莎²,
胡佳慧⁴,
张春红^1,3,5, ,

1.
天津中医药大学第一附属医院针灸临床部，天津 300193
2.
天津中医药大学研究生院，天津 301617
3.
宝安纯中医治疗医院针灸推拿康复科，广东深圳 518000
4.
浙江省人民医院康复科，浙江杭州 310014
5.
国家中医针灸临床医学研究中心，天津 300381

基金项目:

国家重点研发计划项目-政府间国际科技创新合作重点专项项目 2018YFE0181700

详细信息

作者简介:
胡赫其，在读硕士研究生，E-mail: hhq1612211369@163.com

通讯作者:
张春红，教授，博士生导师，E-mail: drzch1113@tjutcm.edu.cn

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- 文章访问数: 610
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- PDF下载量: 19
- 被引次数: 0
出版历程
- 收稿日期: 2021-01-25
- 刊出日期: 2021-03-20

A review on the current situation and prospect of fMRI applying in the neural mechanism research of stroke by acupuncture

Heqi HU^{1,2
,},
Hai LU^1,2,
Lisha HAN²,
Jiahui HU⁴,
Chunhong ZHANG^{1,3,5
, ,}

1.
Department of Acupuncture and Moxibustion, First Teaching Hospital of Tianjin University of Chinese Medicine, Tianjin 300193, China
2.
Graduate School, Tianjin University of Chinese Medicine, Tianjin 301617, China
3.
Department of Acupuncture and Moxibustion, Baoan Pure Traditional Chinese Medicine Treatment Hospital, Shenzhen 518000, China
4.
Department of Rehabilitation, Zhejiang Provincial People's Hospital, Hangzhou 310014, China
5.
National Clinical Medicine Research Center of Traditional Chinese Medicine, Tianjin 300381, China

摘要

摘要: 随着功能磁共振成像分子影像技术的逐步成熟，针刺的脑效应机制研究也步入可视化阶段，且在中风病领域应用较多。功能磁共振成像研究范式主要分为任务态和静息态，分析方法主要包括脑区激活、功能连接、脑网络等。本文根据现有针刺-功能磁共振成像相关文献，归纳出针刺治疗中风偏瘫脑机制的研究进展，针对其试验设计、分析方法等方面分析目前研究可能存在的问题，并展望其应用前景。结果显示针刺可不同程度地激活大脑皮质运动区、感觉区以及小脑、基底节等部位，亦可提高脑区的功能连接，对运动、感觉、语言等脑功能网络发挥一定的调制作用。但仍存在诸多问题需要去改进，未来倡导以中医传统理论为纲，充分融合现代技术，多学科并举，构建针刺治疗中风的特异性脑效应网络。
- 针刺 /
- 中风偏瘫 /
- 功能磁共振成像 /
- 任务态 /
- 静息态 /
- 脑效应机制 /
- 述评
Abstract: As the fMRI molecular imaging technology maturing, the research on the central mechanism for acupuncture effect has also entered the visualization phase, and it is widely used in the field of stroke. At present, fMRI research mainly bases on task-state and resting-state, and analysis methods include brain region activation, functional connection, brain network analysis, etc. Based on the existing literature on acupuncture-fMRI, this review summarizes the progress of central mechanism research on acupuncture in the treatment of stroke, proposes possible problems in the aspects of its experimental design and analysis methods and looks forward to its application prospect. Results show that acupuncture could activate the cerebral cortex motor area, sensory area and cerebellum, basal ganglia to different degrees, and improve the functional connection of some brain regions, regulate brain motor, sensory, language networks. However, there are still many problems that need to be improved. In the future, traditional Chinese medicine theory should be proposed as the outline combine with modern technology through multidisciplinary partnerships to build a specific brain effect network for acupuncture treatment of stroke.
- acupuncture /
- stroke /
- functional magnetic resonance imaging /
- task-state /
- resting-state /
- mechanism of brain effect /
- review

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参考文献(44)

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功能磁共振成像技术在针刺治疗中风偏瘫脑机制研究的现状及前景

doi: 10.12122/j.issn.1674-4500.2021.02.35

作者简介:
胡赫其，在读硕士研究生，E-mail: hhq1612211369@163.com

通讯作者:
张春红，教授，博士生导师，E-mail: drzch1113@tjutcm.edu.cn

计量

A review on the current situation and prospect of fMRI applying in the neural mechanism research of stroke by acupuncture

计量

目录

留言板

功能磁共振成像技术在针刺治疗中风偏瘫脑机制研究的现状及前景

doi: 10.12122/j.issn.1674-4500.2021.02.35

作者简介: 胡赫其，在读硕士研究生，E-mail: hhq1612211369@163.com

通讯作者: 张春红，教授，博士生导师，E-mail: drzch1113@tjutcm.edu.cn

计量

出版历程

A review on the current situation and prospect of fMRI applying in the neural mechanism research of stroke by acupuncture

计量

出版历程

目录

作者简介:
胡赫其，在读硕士研究生，E-mail: hhq1612211369@163.com

通讯作者:
张春红，教授，博士生导师，E-mail: drzch1113@tjutcm.edu.cn