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弥散加权成像ADC值直方图在宫颈癌中的应用进展

穆乃文,  张继

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文章导航 > 分子影像学杂志  > 2020 >  43(4): 709-712
穆乃文, 张继. 弥散加权成像ADC值直方图在宫颈癌中的应用进展[J]. 分子影像学杂志, 2020, 43(4): 709-712. doi: 10.12122/j.issn.1674-4500.2020.04.35
引用本文: 穆乃文, 张继. 弥散加权成像ADC值直方图在宫颈癌中的应用进展[J]. 分子影像学杂志, 2020, 43(4): 709-712. doi: 10.12122/j.issn.1674-4500.2020.04.35
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Naiwen MU, Ji ZHANG. Progress in the application of ADC histogram analysis on diffusion weighted imaging in cervical cancer[J]. Journal of Molecular Imaging, 2020, 43(4): 709-712. doi: 10.12122/j.issn.1674-4500.2020.04.35
Citation: Naiwen MU, Ji ZHANG. Progress in the application of ADC histogram analysis on diffusion weighted imaging in cervical cancer[J]. Journal of Molecular Imaging, 2020, 43(4): 709-712. doi: 10.12122/j.issn.1674-4500.2020.04.35
shu

弥散加权成像ADC值直方图在宫颈癌中的应用进展

doi: 10.12122/j.issn.1674-4500.2020.04.35

  • 泰州市人民医院医学影像科，江苏 泰州 225300

基金项目: 

江苏省高层次卫生人才“六个一工程”拔尖人才科研项目 LGY2018032

江苏省青年医学人才课题 QNRC2016509

江苏省卫生健康委员会科研项目 H2018093

详细信息
    作者简介:

    穆乃文，在读硕士研究生，E-mail: Sivanye1204@163.com

    通讯作者:

    张继，博士，副主任医师，E-mail: zj00151@126.com

Progress in the application of ADC histogram analysis on diffusion weighted imaging in cervical cancer

  • Department of Radiology, Taizhou People's Hospital, Taizhou 225300, China

    摘要
  • 摘要: 宫颈癌的病灶大小、病理类型、分期、组织分化程度以及有无淋巴结转移都会影响患者预后情况。影像学检查可以帮助临床评估宫颈癌的病理特征以及在指导治疗、监测预后方面有重要意义。磁共振DWI序列能够观察细胞内水分子弥散受限情况，较磁共振常规序列更好地发现宫颈癌病灶且对人体无伤害。ADC是弥散加权成像的定量指标，在这基础上，通过高b值获取的ADC值直方图在机体细胞及分子水平上进一步描述肿瘤整体的异质性。据文献报道，ADC值直方图多方面参数能够较好地评估宫颈癌的病理特征（病理类型、组织分化程度、分期）、预测其淋巴结转移、治疗疗效和同步放化疗效果以及预测复发，对机体其他肿瘤的评估也有临床意义。本文就弥散加权成像b值的选择、ADC值直方图的主要参数及ADC值直方图在宫颈癌病理类型、分期、分化程度、淋巴结转移以及预后情况等应用研究方面进行综述。

     

    Abstract: The lesion size, pathological type, stage, tissue differentiation and lymph node metastasis of cervical cancer can affect the prognosis of patients. Imaging examination can evaluate the pathological characteristics of cervical cancer and have great clinical value in guiding treatment and monitoring prognosis. DWI sequence of magnetic resonance can reflect the movement of water molecules, which is better than conventional sequence of magnetic resonance for the detection and examination of cervical cancer lesions, which is no harm to human body. ADC value is a quantitative indicator of diffusionweighted imaging. And on this basis, the histogram of ADC values obtained from high b value can describe the overall heterogeneity of the tumor at the cellular and molecular levels in the body. According to literatures, multiple parameters of ADC value histogram can better evaluate the pathological characteristics (pathological type, tissue differentiation degree, and stage) of cervical cancer, and which is also can predict its lymph node metastasis, therapeutic effect, effect of concurrent chemoradiotherapy, and recurrence. And it has clinical evaluation significance for other tumors in the body. This article reviews the selection of b value for diffusion-weighted imaging, the main parameters of histogram of ADC value, and the pathological type, stage, differentiation degree, lymph node metastasis and prognosis of cervical cancer.

     

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