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Volume 37 Issue 4
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Article Navigation >  Journal of Molecular Imaging  > 2014  >  37(4): 225-228
Weilan XIA, Guangliang ZHANG, Zhiqin LIU. The ExPression and clinical significance of eIF4E and ki67 in patients with endometrosis[J]. Journal of Molecular Imaging, 2014, 37(4): 225-228. doi: 10.3969/j.issn.1674-4500.2014.04.02
Citation: Weilan XIA, Guangliang ZHANG, Zhiqin LIU. The ExPression and clinical significance of eIF4E and ki67 in patients with endometrosis[J]. Journal of Molecular Imaging, 2014, 37(4): 225-228. doi: 10.3969/j.issn.1674-4500.2014.04.02
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The ExPression and clinical significance of eIF4E and ki67 in patients with endometrosis

doi: 10.3969/j.issn.1674-4500.2014.04.02
  • 1.

    shenzhen baoan district maternity and child care, shenzhen 518100, China

  • 2.

    Nafang Hospital of Southern Medical University, Guangzhou 510515, China

  • Received Date: 2014-09-20
  • Publish Date: 2014-10-01
    Abstract
  • Objective To explore the expression and clinical significance of eIF4E and ki67 in endometriosis. Methods The expression of eIF4E and ki67 were detected by immuno- histochemical method of SP in 30 cases of endometriosis and 20 cases of normal endometrium. Results Expression of the three groups showed such sequence as follows about eIF4E and ki67: ectopic endometrium>eutopic endometrium>normal endometrium, there was a significant difference statistically (P<0.01); eIF4E during the reign of normal endometrium and endometrial secretion period is higher than the proliferation period, the differences are significant statistical significance (P<0.05), ki67 in normal secretory phase endometrium group is higher than breeding period (P<0.05), in ectopic group multiplication period is higher than the discharge (P<0.05). The eIF4E and ki67 protein had obvious positive correlation in ectopic endometrial and endometrium (r=0.861, P<0.01; r=0.788, P<0.01), but there was no correlation in the normal endometrium (r=0.297, P=0.207). Conclusion eIF4E and ki67 in endometriosis express obviously increased. The expression of eIF4E and ki67 were positively associated with development and progression of endometriosis.

     

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    • References(8)
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