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Volume 42 Issue 1
Jan.  2019
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Article Contents
Yongyu CHEN, Weijun HUANG, Qinghua XU, Weizhen CUI, Minyan LU, Jie HE. Value of traditional ultrasound, color doppler and ultrasound elastography for prediction axillary lymph node metastasis of breast cancer[J]. Journal of Molecular Imaging, 2019, 42(1): 14-17. doi: 10.12122/j.issn.1674-4500.2019.01.04
Citation: Yongyu CHEN, Weijun HUANG, Qinghua XU, Weizhen CUI, Minyan LU, Jie HE. Value of traditional ultrasound, color doppler and ultrasound elastography for prediction axillary lymph node metastasis of breast cancer[J]. Journal of Molecular Imaging, 2019, 42(1): 14-17. doi: 10.12122/j.issn.1674-4500.2019.01.04

Value of traditional ultrasound, color doppler and ultrasound elastography for prediction axillary lymph node metastasis of breast cancer

doi: 10.12122/j.issn.1674-4500.2019.01.04
  • Received Date: 2018-10-16
  • Publish Date: 2019-01-01
  • Objective To discuss the value of traditional ultrasound, color doppler and ultrasound elastography for diagnosing axillary lymph node (LN) metastasis in breast cancer. Methods Axillary LNs in healthy probands (n=56) and metastatic LNs in breast cancer patients (n=26) were examined by suing traditional ultrasound, color doppler and ultrasound elastography. Short radius, long axis, S/L, cortical thickness, blood flow characteristics and elastic characteristics of all LNs were detected, and then these indicators were compared between the two groups. Receiver operating characteristic(ROC)curve of all above indicators were drawed, and AUC, threshold value, sensitivity (SE) and specificity (SP) were calculated. Moreover, the relationship between cortical thickness and the hardness was studied. Results The short radius, S/L, and cortex thickness of metastatic LNs were all significantly larger than that of non-metastatic LNs (P=0.000). The blood types in metastatic LNs were almost III and IV types. UE displayed that the scores of most metastatic LNs was 3-4, but the scores of most non-metastatic LNs was 1-2 (P<0 01="" the="" se="" of="" short="" radius="" cortical="" thickness="" s="" l="" doppler="" ultrasound="" and="" sonoelastography="" was="" revealed="" to="" be="" 84="" 6="" 84="" 6="" 84="" 6="" 76="" 9="" and="" 84="" 6="" and="" the="" sp="" was="" 73="" 9="" 97="" 8="" 84="" 8="" 95="" 7="" and="" 97="" 8="" respectively="" the="" highest="" se="" and="" sp="" was="" achieved="" by="" the="" b-mode="" cortex="">2.25 mm) and elastographic features (3 score). The cortex thickness had a strong correlation with hardness of LN (r=0.899, P<0.00). Conclusion Cortex thickness and UE of LNs are both feasible method to identify the metastatic LNs from non-etastatic LNs.

     

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