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Volume 42 Issue 1
Jan.  2019
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Article Navigation >  Journal of Molecular Imaging  > 2019  >  42(1): 10-13
Tao GUO, Fei GUO, Jiang WU, Aijun ZHANG. Application of MEG combined with Wada test in preoperative evaluation of epilepsy[J]. Journal of Molecular Imaging, 2019, 42(1): 10-13. doi: 10.12122/j.issn.1674-4500.2019.01.03
Citation: Tao GUO, Fei GUO, Jiang WU, Aijun ZHANG. Application of MEG combined with Wada test in preoperative evaluation of epilepsy[J]. Journal of Molecular Imaging, 2019, 42(1): 10-13. doi: 10.12122/j.issn.1674-4500.2019.01.03
shu

Application of MEG combined with Wada test in preoperative evaluation of epilepsy

doi: 10.12122/j.issn.1674-4500.2019.01.03
  • 1.

    Department of Functional Neurosurgery, The Hebei General Hospital, Shijiazhuang 050051, China

  • 2.

    Department of Drehabilitation, the Second Hospital of Hebei Medical University, Shijiazhuang 050000, China

  • Received Date: 2018-09-14
  • Publish Date: 2019-01-01
    Abstract
  • Objective To investigate the role of MEG combined with Wada test in the assessment of language and memory function in epilepsy patients before surgery. Methods Twenty-six cases of epilepsy patients, preoperative localization of epileptogenic focus and neuropsychological assessment; the combination of MEG and Wada test, to determine the language memory, dominant hemisphere, clear language function area and memory function. IQ, Memory, language function of patients were compared before and 1 year after surgery. Results Twenty-six patients with epilepsy were checked by MEG and Wada test the process smoothly, can lateralization of language and memory of the dominant hemisphere, 20 cases of left hemisphere language dominance, 6 cases were located on the left side on the right side of the. 14 memory of the dominant hemisphere, 8 cases located in the right hemisphere, 4 cases of bilateral.MEG can accurately locate the position of the. WADA language function can be evaluated in patients with memory comparison of memory function. The IQ, memory and language function were measured before and after 1 year. Verbal IQ and total IQ increased (P<0.05), and no significant change in memory quotient and operation IQ (P>0.05). The dominant hemisphere and non dominant hemisphere, memory score was significant (P<0.05). Conclusion Wada test recovered well after operation, without serious language and memory impairment. MEG combined with Wada test can accurately locate the lateral language, memory the dominant hemisphere, and understand the memory function before operation. It is of great significance for guiding the resection range and avoiding postoperative complications.

     

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