双能CT对甲状腺结节诊断价值的研究进展

赵子晗; 陈英敏

doi:10.12122/j.issn.1674-4500.2024.03.19

双能CT对甲状腺结节诊断价值的研究进展

doi: 10.12122/j.issn.1674-4500.2024.03.19

赵子晗^{1, 2,},
陈英敏^1, ,

1.
河北省人民医院医学影像科，河北石家庄 050000
2.
华北理工大学研究生学院，河北唐山 064200

基金项目:

河北省2017年度医学科学研究重点课题 20170005

详细信息

作者简介:
赵子晗，在读硕士研究生，E-mail: 1161324413@qq.com

通讯作者:
陈英敏，博士，E-mail: hbghyingxiang@126.com

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- 文章访问数: 32
- HTML全文浏览量: 15
- PDF下载量: 9
- 被引次数: 0
出版历程
- 收稿日期: 2023-11-17
- 刊出日期: 2024-03-20

Research progress of dual-energy CT in the diagnosis of thyroid nodules

ZHAO Zihan^{1, 2
,},
CHEN Yingmin^{1
, ,}

1.
Department of Radiology, Hebei General Hospital, Shijiazhuang 050000, China
2.
Department of Graduate School, North China University of Science and Technology, Tangshan 064200, China

摘要

摘要: 随着临床诊断技术的发展及体检的普及，甲状腺结节的检出率逐年增加，已成为目前最常见的甲状腺病变之一，无创的影像学检查对其术前诊断有重要作用。双能CT即利用两种不同能谱的X射线能量进行成像，可为甲状腺结节的诊断提供多种不同参数的图像，是常规CT的重要补充。本文对双能CT的基本原理、多参数成像进行了总结，同时对双能CT在甲状腺结节的诊断、鉴别诊断及评估患者是否存在淋巴结转移的价值以及双能CT的其他潜在应用价值的研究现状进行综述，为未来双能CT在甲状腺结节诊断的相关临床应用及研究提供了思路。
- 甲状腺结节 /
- 双能CT /
- 碘 /
- 原子序数
Abstract: Thyroid nodules are now among the most frequent thyroid lesions, with a yearly rise in detection rates due to advancements in clinical diagnostic procedures and the widespread use of physical examinations. A non-invasive imaging assessment is crucial to the preoperative diagnosis of this condition. Dual-energy CT is a valuable addition to standard CT because it uses X-ray radiation from two distinct energy spectrums to offer a range of pictures with varied characteristics for the identification of thyroid nodules. This study provides an overview of dual-energy CT's multi-parameter imaging and basic principles. In order to generate ideas for the clinical application and future research of dual-energy CT in the diagnosis of thyroid nodules, the value of dual-energy CT in the diagnosis, differential diagnosis, and evaluation of lymph node metastasis in patients with thyroid nodules, as well as other potential application values, are reviewed concurrently.
- thyroid nodules /
- dual-energy CT /
- iodine /
- Zeff

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参考文献(54)

[1]	Durante C, Hegedüs L, Czarniecka A, et al. 2023 European Thyroid Association Clinical Practice Guidelines for thyroid nodule management[J]. Eur Thyroid J, 2023, 12(5): e230067.
[2]	Li LQ, Hilmi O, England J, et al. An update on the management of thyroid nodules: rationalising the guidelines[J]. J Laryngol Otol, 2023, 137(9): 965-70. doi: 10.1017/S002221512200233X
[3]	Lu QY, Zhu XM, Wang PS, et al. Comparisons of different approaches and incisions of thyroid surgery and selection strategy[J]. Front Endocrinol, 2023, 14: 1166820. doi: 10.3389/fendo.2023.1166820
[4]	Issa PP, Munshi R, Albuck AL, et al. Recommend with caution: a meta-analysis investigating papillary thyroid carcinoma tumor progression under active surveillance[J]. Am J Otolaryngol, 2023, 44(6): 103994. doi: 10.1016/j.amjoto.2023.103994
[5]	Thyroid cancer incidence statistics[EB/OL]. [2022-12-01]. https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/thyroid-cancer/incidence
[6]	Fontham ET, Correa P. American Society of Preventive Oncology 17th annual meeting[J]. Cancer Epidemiol Biomarkers Prev, 1993, 2(5): 499-504.
[7]	Youssef MR, Attia AS, Omar M, et al. Thyroid lobectomy as a cost-effective approach in low-risk papillary thyroid cancer versus active surveillance[J]. Surgery, 2022, 171(1): 190-6. doi: 10.1016/j.surg.2021.05.057
[8]	Junn JC, Soderlund KA, Glastonbury CM. Imaging of head and neck cancer with CT, MRI, and US[J]. Semin Nucl Med, 2021, 51(1): 3-12. doi: 10.1053/j.semnuclmed.2020.07.005
[9]	Macvanin MT, Gluvic ZM, Zaric BL, et al. New biomarkers: prospect for diagnosis and monitoring of thyroid disease[J]. Front Endocrinol, 2023, 14: 1218320. doi: 10.3389/fendo.2023.1218320
[10]	Alzumaili B, Sadow PM. Update on molecular diagnostics in thyroid pathology: a review[J]. Genes, 2023, 14(7): 1314. doi: 10.3390/genes14071314
[11]	Panda S, Nayak M, Pattanayak L, et al. Reproducibility of cytomorphological diagnosis and assessment of risk of malignancy of thyroid nodules based on the Bethesda system for reporting thyroid cytopathology: a tertiary cancer center perspective[J]. J Microsc Ultrastruct, 2022, 10(4): 174-9. doi: 10.4103/jmau.jmau_88_21
[12]	Dharampal N, Smith K, Harvey A, et al. Cost-effectiveness analysis of molecular testing for cytologically indeterminate thyroid nodules[J]. Le J D'oto Rhino Laryngol De Chir Cervico Faciale, 2022, 51(1): 46.
[13]	Słowińska-Klencka D, Klencki M, Duda-Szymańska J, et al. Optimization of the management of category Ⅲ thyroid nodules using repeat FNA and TIRADS[J]. Cancers, 2022, 14(18): 4489. doi: 10.3390/cancers14184489
[14]	Seminati D, Mane E, Ceola S, et al. An indeterminate for malignancy FNA report does not increase the surgical risk of incidental thyroid carcinoma[J]. Cancers, 2022, 14(21): 5427. doi: 10.3390/cancers14215427
[15]	Seo YL, Yoon DY, Lim KJ, et al. Locally advanced thyroid cancer: can CT help in prediction of extrathyroidal invasion to adjacent structures?[J]. AJR Am J Roentgenol, 2010, 195(3): W240-4. doi: 10.2214/AJR.09.3965
[16]	Jiang LL, Liu DH, Long L, et al. Dual-source dual-energy computed tomography-derived quantitative parameters combined with machine learning for the differential diagnosis of benign and malignant thyroid nodules[J]. Quant Imaging Med Surg, 2022, 12(2): 967-78. doi: 10.21037/qims-21-501
[17]	Dell'Aversana S, Ascione R, de Giorgi M, et al. Dual-energy CT of the heart: a review[J]. J Imaging, 2022, 8(9): 236. . doi: 10.3390/jimaging8090236
[18]	Guerrini S, Bagnacci G, Perrella A, et al. Dual energy CT in oncology: benefits for both patients and radiologists from an emerging quantitative and functional diagnostic technique[J]. Semin Ultrasound CT MR, 2023, 44(3): 205-13. doi: 10.1053/j.sult.2023.03.006
[19]	Ozawa Y, Ohno Y, Nagata H, et al. Advances for pulmonary functional imaging: dual-energy computed tomography for pulmonary functional imaging[J]. Diagnostics, 2023, 13(13): 2295. doi: 10.3390/diagnostics13132295
[20]	Moore J, Remy J, Altschul E, et al. Thoracic applications of spectral CT scan[J]. Chest, 2023. doi: 10.1016/j.chest.2023.07.4225.
[21]	Rapp JB, Biko DM, Siegel MJ. Dual-energy CT for pediatric thoracic imaging: a review[J]. AJR Am J Roentgenol, 2023, 221(4): 526-38. doi: 10.2214/AJR.23.29244
[22]	Wu YY, Wei C, Wang CB, et al. Preoperative prediction of cervical nodal metastasis in papillary thyroid carcinoma: value of quantitative dual-energy CT parameters and qualitative morphologic features[J]. AJR Am J Roentgenol, 2021, 216(5): 1335-43. doi: 10.2214/AJR.20.23516
[23]	Lenga L, Lange M, Martin SS, et al. Head and neck single- and dual-energy CT: differences in radiation dose and image quality of 2nd and 3rd generation dual-source CT[J]. Br J Radiol, 2021, 94(1122): 20210069. doi: 10.1259/bjr.20210069
[24]	Sananmuang T, Agarwal M, Maleki F, et al. Dual energy computed tomography in head and neck imaging: pushing the envelope[J]. Neuroimaging Clin N Am, 2020, 30(3): 311-23. doi: 10.1016/j.nic.2020.04.003
[25]	Hamid S, Nasir MU, So A, et al. Clinical applications of dual-energy CT[J]. Korean J Radiol, 2021, 22(6): 970-82. doi: 10.3348/kjr.2020.0996
[26]	Foti G, Booz C, Buculo GM, et al. Dual-energy CT arthrography: advanced muscolo-skelatal applications in clinical practice[J]. Tomography, 2023, 9(4): 1471-84. doi: 10.3390/tomography9040117
[27]	Sauerbeck J, Adam G, Meyer M. Spectral CT in oncology[J]. Rofo, 2023, 195(1): 21-9. doi: 10.1055/a-1902-9949
[28]	Perrella A, Bagnacci G, Di Meglio N, et al. Thoracic diseases: technique and applications of dual-energy CT[J]. Diagnostics, 2023, 13(14): 2440. doi: 10.3390/diagnostics13142440
[29]	Li M, Zheng XP, Gao F, et al. Spectral CT imaging of intranodular hemorrhage in cases with challenging benign thyroid nodules[J]. Radiol Med, 2016, 121(4): 279-90. doi: 10.1007/s11547-015-0601-6
[30]	Tomita H, Kuno H, Sekiya K, et al. Quantitative assessment of thyroid nodules using dual-energy computed tomography: iodine concentration measurement and multiparametric texture analysis for differentiating between malignant and benign lesions[J]. Int J Endocrinol, 2020, 2020: 5484671.
[31]	Greffier J, Villani N, Defez D, et al. Spectral CT imaging: technical principles of dual-energy CT and multi-energy photon-counting CT[J]. Diagn Interv Imaging, 2023, 104(4): 167-77. doi: 10.1016/j.diii.2022.11.003
[32]	Li F, Huang FL, Liu CM, et al. Parameters of dual-energy CT for the differential diagnosis of thyroid nodules and the indirect prediction of lymph node metastasis in thyroid carcinoma: a retrospective diagnostic study[J]. Gland Surg, 2022, 11(5): 913-26. doi: 10.21037/gs-22-262
[33]	Zopfs D, Reimer RP, Sonnabend K, et al. Intraindividual consistency of iodine concentration in dual-energy computed tomography of the chest and abdomen[J]. Invest Radiol, 2021, 56(3): 181-7. doi: 10.1097/RLI.0000000000000724
[34]	Lee DH, Lee YH, Seo HS, et al. Dual-energy CT iodine quantification for characterizing focal thyroid lesions[J]. Head Neck, 2019, 41(4): 1024-31. doi: 10.1002/hed.25524
[35]	Li M, Zheng XP, Li JY, et al. Dual-energy computed tomography imaging of thyroid nodule specimens: comparison with pathologic findings[J]. Invest Radiol, 2012, 47(1): 58-64. doi: 10.1097/RLI.0b013e318229fef3
[36]	Lam S, Gupta R, Kelly H, et al. Multiparametric evaluation of head and neck squamous cell carcinoma using a single-source dual-energy CT with fast kVp switching: state of the art[J]. Cancers, 2015, 7(4): 2201-16. doi: 10.3390/cancers7040886
[37]	Fernandez-Velilla Cepria E, González-Ballester MÁ, Quera Jordana J, et al. Determination of the optimal range for virtual monoenergetic images in dual-energy CT based on physical quality parameters[J]. Med Phys, 2021, 48(9): 5085-95. doi: 10.1002/mp.15120
[38]	Albrecht MH, Vogl TJ, Martin SS, et al. Review of clinical applications for virtual monoenergetic dual-energy CT[J]. Radiology, 2019, 293(2): 260-71. doi: 10.1148/radiol.2019182297
[39]	贾永军, 张志远, 潘自兵, 等. CT能谱成像对常见甲状腺结节良恶性鉴别价值的初步研究[J]. 实用放射学杂志. 2014, 30(3): 394-8. doi: 10.3969/j.issn.1002-1671.2014.03.007
[40]	Li L, Wang Y, Luo DH, et al. Diagnostic value of single-source dual-energy spectral computed tomography for papillary thyroid microcarcinomas[J]. J Xray Sci Technol, 2017, 25(5): 793-802.
[41]	Shi RY, Yao QY, Zhou QY, et al. Preliminary study of diffusion kurtosis imaging in thyroid nodules and its histopathologic correlation[J]. Eur Radiol, 2017, 27(11): 4710-20. doi: 10.1007/s00330-017-4874-0
[42]	金梅, 刘力, 林奕军, 等. 双源CT碘图与能谱曲线技术在甲状腺结节鉴别诊断中的应用[J]. 医学影像学杂志, 2016, 26(12): 2203-7. https://www.cnki.com.cn/Article/CJFDTOTAL-XYXZ201612018.htm
[43]	杨凯. 双源CT双能量扫描对于甲状腺结节良恶性鉴别诊断的应用价值[D]. 石家庄: 河北医科大学, 2012.
[44]	Haugen BR, Alexander EK, Bible KC, et al. 2015 American thyroid association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American thyroid association guidelines task force on thyroid nodules and differentiated thyroid cancer[J]. Thyroid, 2016, 26(1): 1-133. doi: 10.1089/thy.2015.0020
[45]	Park JE, Lee JH, Ryu KH, et al. Improved diagnostic accuracy using arterial phase CT for lateral cervical lymph node metastasis from papillary thyroid cancer[J]. AJNR Am J Neuroradiol, 2017, 38(4): 782-8. doi: 10.3174/ajnr.A5054
[46]	Zhou Y, Su GY, Hu H, et al. Radiomics analysis of dual-energy CT-derived iodine maps for diagnosing metastatic cervical lymph nodes in patients with papillary thyroid cancer[J]. Eur Radiol, 2020, 30(11): 6251-62. doi: 10.1007/s00330-020-06866-x
[47]	Yoon J, Choi Y, Jang J, et al. Preoperative assessment of cervical lymph node metastases in patients with papillary thyroid carcinoma: incremental diagnostic value of dual-energy CT combined with ultrasound[J]. PLoS One, 2021, 16(12): e0261233. doi: 10.1371/journal.pone.0261233
[48]	Liu XW, Ouyang D, Li H, et al. Papillary thyroid cancer: dual-energy spectral CT quantitative parameters for preoperative diagnosis of metastasis to the cervical lymph nodes[J]. Radiology, 2015, 275(1): 167-76. doi: 10.1148/radiol.14140481
[49]	Baba A, Kurokawa R, Kurokawa M, et al. Dual-energy computed tomography for improved visualization of internal jugular chain neck lymph node metastasis and nodal necrosis in head and neck squamous cell carcinoma[J]. Jpn J Radiol, 2023, 41(12): 1351-8. doi: 10.1007/s11604-023-01460-9
[50]	Lam S, Gupta R, Levental M, et al. Optimal virtual monochromatic images for evaluation of normal tissues and head and neck cancer using dual-energy CT[J]. AJNR Am J Neuroradiol, 2015, 36(8): 1518-24. doi: 10.3174/ajnr.A4314
[51]	Yang GCH, Stern CM, Messina AV. Cystic papillary thyroid carcinoma in fine needle aspiration may represent a subset of the encapsulated variant in WHO classification[J]. Diagn Cytopathol, 2010, 38(10): 721-6. doi: 10.1002/dc.21282
[52]	Kim DW, Lee EJ, In HS, et al. Sonographic differentiation of partially cystic thyroid nodules: a prospective study[J]. AJNR Am J Neuroradiol, 2010, 31(10): 1961-6. doi: 10.3174/ajnr.A2204
[53]	Li HW, Wu XW, Liu B, et al. Clinical values of of gemstone spectral CT in diagnosing thyroid disease[J]. J Xray Sci Technol, 2015, 23(1): 45-56.
[54]	Tawfik AM, Razek AA, Kerl JM, et al. Comparison of dual-energy CT-derived iodine content and iodine overlay of normal, inflammatory and metastatic squamous cell carcinoma cervical lymph nodes[J]. Eur Radiol, 2014, 24(3): 574-80.

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双能CT对甲状腺结节诊断价值的研究进展

doi: 10.12122/j.issn.1674-4500.2024.03.19

作者简介:
赵子晗，在读硕士研究生，E-mail: 1161324413@qq.com

通讯作者:
陈英敏，博士，E-mail: hbghyingxiang@126.com

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Research progress of dual-energy CT in the diagnosis of thyroid nodules

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目录

留言板

双能CT对甲状腺结节诊断价值的研究进展

doi: 10.12122/j.issn.1674-4500.2024.03.19

作者简介: 赵子晗，在读硕士研究生，E-mail: 1161324413@qq.com

通讯作者: 陈英敏，博士，E-mail: hbghyingxiang@126.com

计量

出版历程

Research progress of dual-energy CT in the diagnosis of thyroid nodules

计量

出版历程

目录

作者简介:
赵子晗，在读硕士研究生，E-mail: 1161324413@qq.com

通讯作者:
陈英敏，博士，E-mail: hbghyingxiang@126.com