The value of 256-slice iCT1024 matrix perfusion imaging in the diagnosis of solitary pulmonary nodules
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摘要:
目的 探讨飞利浦256层iCT1024矩阵灌注成像在孤立性肺结节诊断中的价值。 方法 对38例孤立性肺结节患者行灌注扫描，扫描数据传至EBW工作站，用肺结节分析软件进行图像分析，获取血流量（BF）、血容量（BV）、平均通过时间（MTT），增强峰值（PH）以及SPN与主动脉PH值比值（S/A）等指标。进行统计学分析，并与病理结果进行对照。 结果 恶性和炎性结节的BV、PH和S/A比值明显高于良性结节（P＜0.01），而恶性与炎性之间的BV、PH、S/A比值差异则无统计意义（P＞0.05）。恶性结节、炎性结节、良性结节的TDC形态不同。 结论 256层iCT1024矩阵灌注成像有助于鉴别孤立性肺结节的良、恶性。 Abstract:Objective To investigate the value of Philips 256-slice iCT1024 matrix perfusion imaging in the diagnosis of solitarypulmonary nodules (SPN). Methods A total of 38 patients with SPN underwent perfusion scan, the scaned data was sended toEBW workstation, the images were analysed by pulmonary nodules analysis software to obtain the indexes of blood flow (BF),blood volume (BV), mean through time (MTT), peak height (PH) and ratio of SPN to aortic PH (S/A). The indexes underwentstatistical analysis, and were compared with pathological results. Results The BV, PH and S/A ratio values of malignant andinflammatory nodules were significantly higher than those of benign nodules (P<0.01), while the BV, PH and S/A ratio valuesbetween malignant and inflammatory nodules were no statistically significant (P>0.05). The TDC appeared different formalignant,inflammatory and benign nodules. Conclusion 256-slice iCT1024 matrix perfusion imaging can help to identify thebenign or malignant of SPN. -
Key words:
- 1024 matrix /
- perfusion /
- solitary pulmonary nodule
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表 1 38例SPN的CT灌注结果（n=38）
类型 n BF（mL/min/100 g） BV（mL/100 g） MTT（s） PS（mL/min/100 g） 恶性结节 28 87.33±4.56 16.75±3.88 22.25±8.65 28.33±4.67 炎性结节 4 92.11±6.54 13.65±6.51 16.34±2.64 14.13±1.21 良性结节 6 55.28±0.87 4.51±0.57 11.05±1.99 11.38±2.13 
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表 2 38例SPN患者结节特征参数值统计表（n=38）
类型 n 强化值
（Hu）结节动脉强化值比
（S/A）达峰值时间
（MS）恶性结节 28 58.59±3.67 0.18±0.03 30527±834 炎性结节 4 10.31±9.95 0.17±0.04 28366±11598 良性结节 6 9.30±1.67 0.05±0.01 16356±10378
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