Research of nasal resistance changes of allergic rhinitis before and after desensitization treatment
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摘要:
目的观察比较安脱达皮下注射免疫治疗变应性鼻炎前后鼻阻力的动态变化。 方法追踪观察43例成人变应性鼻炎患者，严格按安脱达脱敏治疗，记录治疗前、治疗15周后、治疗1年后症状体征评分，鼻阻力分析比较各期症状体征评分、鼻阻力。 结果尘螨皮下免疫治疗前与治疗15周后、治疗1年后症状体征评分（单个症状评分、总症状评分），鼻阻力比较有统计学差异（F=318.811，P < 0.001）。鼻阻力与症状体征总分无相关性（r=-0.77，P>0.5）（r=0.45，P < 0.5）。 结论鼻阻力随变应性鼻炎免疫治疗深入逐渐改善，连续动态的检测鼻阻力可客观判断疗效，可作为症状体征评分的补充。 Abstract:ObjectiveTo compare dynamic change of nasal resistance before and after ATD SCIT. Method43 cases of adult patients with allergic rhinitis, tracking ATD SCIT, recording symptom and sign scores、nasal resistance before and15 weeks after treatment, 1 year after treatment. Compare symptom and sign scores, nasal resistance all periods. Resultsymptom and sign scores (single symptom scores, total symptom scores)、nasal resistance before dust mites SCIT and 15 weeks after treatment, 1 year after treatment was statistically significant (F=318.811, P < 0.001). Nasal resistance with symptom and sign scores is no correlation (r=0.77, P>0.5). Conclusionnasal resistance gradually improve with allergic rhinitis immunotherapy, but no correlation with symptom and sign scores, continuous dynamic detection of nasal resistance can assess effect objectively, can be used to supple the symptom and sign scores. -
Key words:
- Allergic rhinitis /
- nasal resistance /
- desensitization treatment
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