3D-ASL与多模态磁共振在诊断短暂性脑缺血发作中的应用研究进展

摘要: 短暂性脑缺血发作（TIA）被定义为脑、脊髓或视网膜局灶性缺血所致的、不伴急性梗死的短暂性神经功能障碍，判断TIA或急性脑梗死鉴别诊断的唯一依据是有无梗死，与临床症状持续时间无关。临床上TIA常依靠临床症状进行诊断，常规MR检查一般多无阳性发现。三维动脉自旋标记（3D-ASL）是目前比较流行且突出的灌注成像技术，可以产生定量的灌注图像，作为研究大脑功能的一种强有力的临床手段而日益受到重视。临床研究表明3D-ASL可以提供诊断TIA的依据，当联合DWI、MRA或者DSC-PWI检查时，对TIA的诊断、治疗、预后、风险评估等提供可靠依据，且对于不同身体耐受情况的患者可以选择不同的诊断模式。本文将对不同身体耐受情况TIA患者进行3D-ASL与DWI、MRA、DSC-PWI联合诊断的现状进行综述。
- 三维动脉自旋标记 /
- 多模态磁共振 /
- 短暂性脑缺血发作
Abstract: Transient ischemic attack (TIA) is defined as transient neurological dysfunction caused by focal ischemia of brain, spinal cord or retina without acute infarction. The only basis for the differential diagnosis of TIA or acute cerebral infarction is whether there is infarction or not, which has no relationship with the duration of clinical symptoms. In clinic, TIA is usually diagnosed by clinical symptoms, and no positive findings are found in routine MR examination. 3D-ASL is a relatively popular and prominent perfusion imaging technology, which can produce quantitative perfusion images. As a powerful clinical means to study brain function, 3D-arterial spin labeling (3D-ASL) has been paid more and more attention and is in constant development. Clinical studies have shown that 3d- asl can provide the basis for the diagnosis of TIA. When combined with DWI, MRA or DSC-PWI, it can provide reliable basis for the diagnosis, treatment, prognosis and risk assessment of TIA, and different diagnostic modes can be selected for patients with different physical tolerance. Therefore, this paper will review the current situation of 3D-ASL combined with multimodal MRI in TIA patients with different physical tolerance.
- 3D-arterial spin labeling /
- multimodal MR /
- transient ischemic attack

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参考文献(28)

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3D-ASL与多模态磁共振在诊断短暂性脑缺血发作中的应用研究进展

doi: 10.12122/j.issn.1674-4500.2021.01.43

作者简介:
邹春霞，硕士，住院医师，E-mail: 1986923873@qq.com

通讯作者:
冯静，主治医师E-mail: 29617524@qq.com

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Research progress in the application of 3D-ASL and multimodal MR in diagnosis of TIA

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3D-ASL与多模态磁共振在诊断短暂性脑缺血发作中的应用研究进展

doi: 10.12122/j.issn.1674-4500.2021.01.43

作者简介: 邹春霞，硕士，住院医师，E-mail: 1986923873@qq.com

通讯作者: 冯静，主治医师E-mail: 29617524@qq.com

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Research progress in the application of 3D-ASL and multimodal MR in diagnosis of TIA

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出版历程

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作者简介:
邹春霞，硕士，住院医师，E-mail: 1986923873@qq.com

通讯作者:
冯静，主治医师E-mail: 29617524@qq.com