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小细胞肺癌的生物学研究及其临床治疗进展

苏晓芳 郭凌宏 黄文华

苏晓芳, 郭凌宏, 黄文华. 小细胞肺癌的生物学研究及其临床治疗进展[J]. 分子影像学杂志, 2018, 41(4): 488-492. doi: 10.12122/j.issn.1674-4500.2018.04.16
引用本文: 苏晓芳, 郭凌宏, 黄文华. 小细胞肺癌的生物学研究及其临床治疗进展[J]. 分子影像学杂志, 2018, 41(4): 488-492. doi: 10.12122/j.issn.1674-4500.2018.04.16
Xiaofang SU, Linghong GUO, Wenhua HUANG. Biology of SCLC: the implications and the progress for the clinical therapy[J]. Journal of Molecular Imaging, 2018, 41(4): 488-492. doi: 10.12122/j.issn.1674-4500.2018.04.16
Citation: Xiaofang SU, Linghong GUO, Wenhua HUANG. Biology of SCLC: the implications and the progress for the clinical therapy[J]. Journal of Molecular Imaging, 2018, 41(4): 488-492. doi: 10.12122/j.issn.1674-4500.2018.04.16

小细胞肺癌的生物学研究及其临床治疗进展

doi: 10.12122/j.issn.1674-4500.2018.04.16
基金项目: 国家自然科学基金(61427807);福建省引进重大研发机构资助项目(2012I2004);南方医科大学2014年省级大学生创新训练计划项目(201412121103)
详细信息
    作者简介:

    苏晓芳,本科,E-mail: 1587258375@qq.com

    通讯作者:

    黄文华,教授,E-mail: 13822232749@139.com

Biology of SCLC: the implications and the progress for the clinical therapy

  • 摘要: 肺癌是全球几大恶性肿瘤之一,在我国居于恶性肿瘤发病及死亡首位。小细胞肺癌是肺内分泌肿瘤的一种,具有侵袭性强、易复发、易转移、预后不良等特征。而临床上小细胞肺癌的一线治疗方案仍未取得突破性的进展,主要仍以化疗为主,辅以放疗等综合治疗。虽然,小细胞肺癌对化疗反应敏感,但80%局限期小细胞肺癌及几乎所有广泛期小细胞肺癌都会发生肿瘤复发及进展,且化疗的毒副作用大。生物信息学及分子生物技术的发展为癌症的诊治提供更为广泛的空间,其中生物治疗方法为近年研究的热点之一,尤其是免疫治疗,特别是研究一些免疫检查点抑制剂以达到抗癌的作用。本文旨在阐述小细胞肺癌生物学研究及其治疗进展。

     

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  • 收稿日期:  2018-10-02
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