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Volume 41 Issue 2
May  2018
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Huajun DENG, Zhijia MA. Application of dexamethasone plus ropivacaine for continuous femoral nerve block in postoperative analgesia of patients undergoing total knee arthroplasty[J]. Journal of Molecular Imaging, 2018, 41(2): 245-248. doi: 10.3969/j.issn.1674-4500.2018.02.25
Citation: Huajun DENG, Zhijia MA. Application of dexamethasone plus ropivacaine for continuous femoral nerve block in postoperative analgesia of patients undergoing total knee arthroplasty[J]. Journal of Molecular Imaging, 2018, 41(2): 245-248. doi: 10.3969/j.issn.1674-4500.2018.02.25

Application of dexamethasone plus ropivacaine for continuous femoral nerve block in postoperative analgesia of patients undergoing total knee arthroplasty

doi: 10.3969/j.issn.1674-4500.2018.02.25
  • Received Date: 2018-02-09
  • Publish Date: 2018-04-01
  • Objective To compare the analgesic effect of dexamethasone plus ropivacaine and ropivacaine for continuous femoral nerve block in postoperative analgesia of patients undergoing unilateral total knee arthroplasty (TKA). Methods Forty patients undergoing TKA were randomly assigned to the control group and the experimental group, and were given continuous femoral nerve block guided by b-ultrasound. Patients in the control group were given 150 ml 2.5 g/L ropivacaine and those in the experimental group were given 150 ml 2.5 g/L ropivacaine and 0.1 g/L dexamethasone. Visual analog scale (VAS) in rest and in active and passive rehabilitation exercise, morphine consumption, the range of active knee flexion and opioids-related adverse effects were recorded at different time points. Results Postoperative VAS scores in rest at 6, 12, 24, 48 and 72 h and in active and passive rehabilitation exercise at 24, 48 and 72 h in the experimental group were significantly lower than those in the control group (P<0.05). Morphine consumptions in periods of time after 6 h and in 72 h were significantly less in the the experimental group than those in the control group (P<0.05). The postoperative range of active knee flexions at 24, 48 and 72 h in the experimental group were significantly larger than those in the control group (P<0.05). Moreover, the rate of adverse effects was 15% in the experimental group while that was 30% in the control group, and there was no significant difference between them (P>0.05). Conclusion Dexamethasone plus ropivacaine provided better postoperative analgesia than ropivacaine for continuous femoral nerve block in patients undergoing TKA. With low rate of adverse effects, it could enhance recovery after surgery and reduce opioid consumptions, which is worth popularizing.

     

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