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Volume 41 Issue 2
May  2018
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Article Navigation >  Journal of Molecular Imaging  > 2018  >  41(2): 241-244
Chengqiu ZHONG, Xubo WAN. Effect of the treatment of gestational diabetes on the offspring’s childhood obesity[J]. Journal of Molecular Imaging, 2018, 41(2): 241-244. doi: 10.3969/j.issn.1674-4500.2018.02.24
Citation: Chengqiu ZHONG, Xubo WAN. Effect of the treatment of gestational diabetes on the offspring’s childhood obesity[J]. Journal of Molecular Imaging, 2018, 41(2): 241-244. doi: 10.3969/j.issn.1674-4500.2018.02.24
shu

Effect of the treatment of gestational diabetes on the offspring’s childhood obesity

doi: 10.3969/j.issn.1674-4500.2018.02.24

  • Sichuan Jinxin Women and Children’s Hospital, Chengdu 610016, China

  • Received Date: 2018-02-18
  • Publish Date: 2018-04-01
    Abstract
  • Objective To explore the effect of the treatment of gestational diabetes mellitus (GDM) on the offspring’s childhood obesity. Methods 137 women diagnosed with GDM in our hospital were enrolled, and there were similar baseline characteristics between the maternal follow treated and untreated groups. A follow-up study was carried on the offspring of the abovementioned women 5-6 years after their deliveries in our hospital. Height, weight, blood pressure, waist circumference, fasting glucose, fasting insulin, triglycerides, and HDL cholesterol of their offspring were measured. Results The frequency of BMI>P95 (8.8% and 9.5%,P=0.78) and BMI>P85 (16.8% and 19.7%,P=0.65) in their offspring was not significantly different in treated and untreated group. The difference of BMI z score, log waist circumference, log triglycerides, HDL cholesterol, blood pressure, or log HOMA-estimated insulin resistance (HOMA-IR) between treated and untreated group were not significant (P>0.05). However, the difference of fasting glucose and log HOMA-IR between the female offspring of each group was significant(P for interaction = 0.002 and 0.02, respectively) in female offspring. Conclusions Although the treatment of gestational diabetes can reduce the fasting glucose of the female offspring, the overall incident of childhood obesity has not been improved.

     

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