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Volume 41 Issue 2
May  2018
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Article Navigation >  Journal of Molecular Imaging  > 2018  >  41(2): 142-146
Zengkun LIN, Hong WEN. Value of B-flow and contrast-enhanced ultrasonography in the imaging of synovial blood flow of small joints of wrist and hand in rheumatoid arthritis[J]. Journal of Molecular Imaging, 2018, 41(2): 142-146. doi: 10.3969/j.issn.1674-4500.2018.02.02
Citation: Zengkun LIN, Hong WEN. Value of B-flow and contrast-enhanced ultrasonography in the imaging of synovial blood flow of small joints of wrist and hand in rheumatoid arthritis[J]. Journal of Molecular Imaging, 2018, 41(2): 142-146. doi: 10.3969/j.issn.1674-4500.2018.02.02
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Value of B-flow and contrast-enhanced ultrasonography in the imaging of synovial blood flow of small joints of wrist and hand in rheumatoid arthritis

doi: 10.3969/j.issn.1674-4500.2018.02.02

  • Department of Ultrasound, Huizhou Municipal Central Hospital, Huizhou 516001, China

  • Received Date: 2018-01-16
  • Publish Date: 2018-04-01
    Abstract
  • Objective To explore the value of Color Doppler Flow Imaging technology (CDFI), B-flow and contrast-enhanced ultrasound (CEUS) in the blood flow imaging of synovial lesion in small joints of wrist and hand with rheumatoid arthritis (RA). Methods A GE Logiq S8 18M polo stick-form linear array probe was used to examine the wrist joints, metacarpophalangeal joints and proximal interphalangeal joints of 240 RA patients. CDFI was applied to detect the synovial blood flow, and the result was classified into 0 ~ 3 according to Szkudlarek semi-quantitative method. For 250 cases whose synovial blood flow were over level 1, spectral doppler technology was applied to measure the resistance index (RI) of synovial pannus which was then used for the correlation analysis with the semi-quantitative method, and B-flow Ultrasound Imaging technology was used to examine the blood flow of synovium. The results of B-flow and CDFI were compared to study the difference of display rate between two devices. For 90 cases whose synovium of lesion joints had no blood signals as CDFI showed, CEUS was used and the result of which was compared with that of B-flow to study the difference of detection rate of synovial pannus. Results The synovium of 240 RA samples all appeared low heterogeneous echo, among which blood flow of synovium was detected in 200 RA cases (82 of level 1, 72 of level 2, 46 of level 3). As the blood flow classification increased, RI decreased gradually; therefore, blood flow classification correlated negatively with RI. 2. The detection rates of blood flow in synovial lesion joints of RA patients displayed by CDFI and B-flows were (154/250) and (206/250), and the difference was significant (P<0.05).As for the 90 cases whose synovium of lesion joints had no blood signals as CDFI showed, the blood flow detection rates by B-flow and CEUS were (56／90) and (74／90), and the difference was significant (P<0.05). Conclusions Compared with CDFI, B-flow and CEUS have higher detection rates of blood flow of RA synovium, especially CEUS, and they play an important role in the early diagnosis of RA and even the determination of therapeutic endpoints. RI of synovial pannus can effectively evaluate the activity of RA, and has guiding significance to clinical diagnosis, therapy and medication.

     

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