Application prospect of 3D bio-printing in maxillofacial region
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摘要: 3D生物打印是利用数字化影像技术将临床获取的医学影像转换为二维模式,供计算机辅助设计/计算机辅助制造软件进行逐层打印并叠加的过程。这种自下而上的打印过程中,生物材料和活细胞被精确地带到目标位置,实现复杂结构的精密打印。基于3D打印的高度灵活性,利用该高新技术可以个性化修复患者因创伤、肿瘤、遗传等问题引起的诸如骨缺损、软组织缺损等问题。因此3D打印成为近年来的研究热点之一。本文概述了3D生物打印目前的研究进展,对3D生物打印的特点、打印方式进行论述,综述3D生物打印在口腔颌面部的临床应用,对其未来发展前景进行了总结。Abstract: 3D bio-printing, a process of converting medical images acquired from clinical data into two-dimensional mode using digital imaging technology, is used for computer-aided design/computer-aided manufacturing software to print and overlay layer by layer. In this bottom-up printing process, biomaterials and living cells are precisely mapped to the target location to achieve sophisticated printing of complex structures. Based on the high flexibility of 3D printing, this high and new technology can be used to repair the problems caused by trauma, tumor or heredity. Therefore, 3D-bioprinting have become a research attraction in recent years. This paper summarized recent research progress of pure biological material in 3D bio-printing and cell-printing, including the characteristics of 3D-biological printing and the way of 3D-biological printing as well as the clinical maxillofacial application and its future development.
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Key words:
- 3D bio-printing /
- cell printing /
- oral medical biomaterials /
- organ printing
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