低强度聚焦超声在神经调控中的作用机制及其应用前景

曹佳智; 黄林; 凌文武

doi:10.12122/j.issn.1674-4500.2024.10.20

低强度聚焦超声在神经调控中的作用机制及其应用前景

doi: 10.12122/j.issn.1674-4500.2024.10.20

曹佳智^1,,
黄林²,
凌文武^1, ,

1.
四川大学华西医院超声医学科，四川成都 610041
2.
电子科技大学电子科学与工程学院，四川成都 611731

基金项目:

国防科技创新特区163计划 18-163-21-TS-001-050-01

详细信息

作者简介:
曹佳智，硕士，技师，E-mail: caojiazhicjz@163.com

通讯作者:
凌文武，博士，副教授，E-mail: lingwenwubing@163.com

计量
- 文章访问数: 87
- HTML全文浏览量: 33
- PDF下载量: 14
- 被引次数: 0
出版历程
- 收稿日期: 2024-06-25
- 网络出版日期: 2024-11-02
- 刊出日期: 2024-10-20

The mechanism and application prospect of low-intensity focused ultrasound in neuromodulation

CAO Jiazhi^1
,,
HUANG Lin²,
LING Wenwu^{1
, ,}

1.
Department of Medical Ultrasound, West China Hospital of Sichuan University, Chengdu 610041, China
2.
School of Electronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu 611731, China

摘要

摘要: 随着脑科学计划的推进，大脑相关研究已成为科研热点，与其相关的神经调控是目前研究的前沿方向。相比传统的神经调控手段，低强度聚焦超声（LIFU）作为一种新兴的神经调控技术，具有无创、可逆、可靶向大脑深层结构等优点，已被国内外学者广泛研究，但关于LIFU神经调控的具体机制还不十分清晰，而机制的阐明对其在相关领域的应用具有指导意义。本文就近年来LIFU神经调控的作用机制的研究进展进行简要综述，并且简要梳理了超声在神经系统的应用，以期为超声神经调控的后续基础和临床研究提供参考。
- 低强度聚焦超声 /
- 神经调控 /
- 作用机制 /
- 超声
Abstract: The proposal of the Brain Science Project has made brain- related research a hot topic, and its related neuromodulation is a frontier and hot topic of current research. Compared with traditional neuromodulation methods, Low Intensity Focused Ultrasound (LIFU), as an emerging neuromodulation technology, has the advantages of non- invasive, reversible, and targetable deep brain structures. It has been extensively studied by scholars at home and abroad. However, the specific mechanism of LIFU neuromodulation is not very clear, and the clarification of the mechanism has guiding significance for its application in related fields. This article briefly summarizes the research progress on the mechanism of LIFU neural modulation in recent years, and briefly outlines the application of ultrasound in the nervous system, aiming to provide references for the subsequent basic and clinical research on ultrasound neural modulation.
- low intensity focused ultrasound /
- neuromodulation /
- mechanism /
- ultrasound

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