Comparation of MRI 3D-WE sequence in ankle cartilage imaging
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摘要:
目的 通过比较3种踝关节三维水激发序列中,软骨的信噪比(SNR)和对比噪声比(CNR),分析3D MR序列显示关节软骨的优缺点。 方法 选取30名志愿者(年龄18~25周岁),均进行3种3D踝关节软骨MRI扫描,利用Skyra 3.0T MR和头颈联合Head/Neck 18通道线圈。双回波稳态进动(DESS)序列、多回波数据图像重合(MEDIC)序列、三维容积内插快速扰相,容积内插体部检查(VIBE)。在踝关节胫距关节中央层面分别测量踝关节软骨、肌间脂肪、距骨骨髓、拇长屈肌和软骨滑液的SNR、背景噪声信号强度,通过软件计算软骨SNR和软骨-脂肪(CNRca- Fat)、软骨-骨髓(CNRca- Bone)、软骨-肌肉(CNRca- Muscle)和软骨-滑液(CNRca-Fluid),同时对不同序列显示踝关节软骨的能力进行评价。 结果 MEDIC序列、VIBE序列的SNR高于DESS序列,差异有统计学意义(P < 0.05)。VIBE序列、DESS序列、MEDIC序列的CNRca-Fat差异有统计学意义(12.75±2.78 vs 6.72±2.09 vs 15.07± 3.89,P < 0.05)。VIBE序列、DESS序列、MEDIC序列的CNRca-Bone差异有统计学意义(12.88±2.46 vs 7.32±2.07 vs -1.75±1.95,P < 0.05),CNRca-Muscle差异有统计学意义(2.28±0.71 vs 1.17±1.27 vs -1.15±2.17,P < 0.05),CNRca-Fluid差异有统计学意义(1.37±1.31 vs -5.62±6.01 vs -3.28±3.06,P < 0.05)。 结论 与DESS、MEDIC序列相比,VIBE能更为清晰地显示踝关节软骨的细微解剖结构及边缘,与周边关节腔积液分界更清楚,能够清晰准确地显示踝关节软骨各种三维数据,是软骨厚度、体积等测量计算的准确工具。 Abstract:Objective To analyze the advantages and disadvantages of 3D MR sequences in displaying articular cartilage by comparing the signal to noise ratio (SNR) and contrast to noise ratio (CNR) of cartilage in three kinds of ankle 3D water excitation (3D-WE) sequences. Methods Thirty volunteers (aged 18-25 years old) were selected to perform three kinds of 3D MRI scans of ankle cartilage, using Siemens skyra 3.0T MR and head/neck 18 channel coil. Dual echo steady state (DESS) sequence, multi echo data image combination (MEDIC) sequence, three-dimensional volume interpolation fast phase scrambling, volume interpolated body examination (VIBE). The SNRca-x and signal intensity of ankle cartilage, fat, bone, muscle, fluid were measured at the central level of the tibiotalar joint of the ankle joint. The cartilage of SNR and CNRca-Fat, CNRca-Bone, CNRca-Muscle and CNRa-Fluid were calculated by computer. At the same time, the ability of different sequences to display ankle cartilage is evaluated. Results The value of SNR of MEDIC and VIBE were significantly higher than that of DESS (P < 0.05). The values of CNRca-Fat between VIBE, DESS and MEDIC were significantly different(12.75±2.78 vs 6.72±2.09 vs 15.07±3.89, P < 0.05). The value of CNRca-Bone between VIBE, DESS and MEDIC were significantly different(12.88±2.46 vs 7.32±2.07 vs -1.75± 1.95, P < 0.05).The value of CNRca-Muscle between VIBE, DESS and MEDIC were significantly different(2.28 ± 0.71 vs 1.17 ± 1.27 vs -1.15±2.17, P < 0.05). The CNRca-Fluid value between VIBE, DESS and MEDIC were significantly different(1.37±1.31 vs -5.62±6.01 vs -3.28 ± 3.06, P < 0.05). Conclusion Compared with DESS and MEDIC sequences, VIBE can more clearly display the fine anatomical structure and edge of ankle cartilage. The boundary with the surrounding joint cavity effusion is clearer. It can clearly and accurately display various three-dimensional data of ankle cartilage. It is an accurate tool for measuring and calculating the thickness and volume of cartilage. -
Key words:
- ankle /
- cartilage /
- 3D-WE sequence /
- signal to noise ratio /
- contrast to noise ratio
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表 1 MR扫描序列及参数列表
Table 1. MR scanning sequence and parameter list
序列 TR(ms) TE(ms) Flip(°) 视野(mm) 矩阵 层厚(mm) 层间距(mm) TA(min) 3D-VIBE 10.5 4.92 10 150 256×256 0.6 0 2∶25 3D-DESS 13.48 5.0 28 150 256×256 0.6 0 3∶29 3D-MEDIC 29.0 16.0 10 150 256×256 0.6 0 3∶50 3D-DESS:3D双回波稳态进动; 3D-MEDIC:3D多回波数据图像重合; 3D-VIBE:3D多回波数据图像重合. 表 2 不同MR-3D序列关节软骨与其他组织的CNR
Table 2. CNR of articular cartilage and other tissues with different MR-3D sequences (Mean±SD)
其他组织 VIBE DESS MEDIC F P CNRCA-FAT 12.75±2.78 6.72±2.09 15.07±3.89 61.50 < 0.001 CNRCA-BONE 12.88±2.46 7.32±2.07 -1.75±1.95 346.53 < 0.001 CNRCA-MUSCLE 2.28±0.71 1.17±1.27 -1.15±2.17 40.39 < 0.001 CNRCA-FLUID 1.37±1.31 -5.62±6.01 -3.28±3.06 26.56 < 0.001 CNRca-Fat:软骨-脂肪; CNRca-Bone:软骨-骨髓; CNRca-Muscle:软骨-肌肉; CNRca-Fluid:软骨-滑液. -
[1] Baillie P, Cook J, Ferrar K, et al. Magnetic resonance imaging findings associated with posterior ankle impingement syndrome are prevalent in elite ballet dancers and athletes[J]. Skeletal Radiol, 2021, 50(12): 2423-31. doi: 10.1007/s00256-021-03811-x [2] Dahmen J, Karlsson J, Stufkens SAS, et al. The ankle cartilage cascade: incremental cartilage damage in the ankle joint[J]. Knee Surg Sports Traumatol Arthrosc, 2021, 29(11): 3503-7. doi: 10.1007/s00167-021-06755-w [3] Horiuchi S, Yu HJ, Luk A, et al. T1rho and T2 mapping of ankle cartilage of female and male ballet dancers[J]. Acta Radiol, 2020, 61(10): 1365-76. doi: 10.1177/0284185120902381 [4] Shi L, Wang KX, Yu JH, et al. Correction to: relationship between magnetic resonance T2-mapping and matrix metalloproteinase 1, 3 in knee osteoarthritis[J]. JOIO, 2021, 55(4): 983-6. doi: 10.1007/s43465-020-00310-4 [5] 曾勇, 杨友林, 程春. 空军地勤人员军事训练致踝关节损伤153例MRI特点分析[J]. 人民军医, 2020, 63(2): 143-6. https://www.cnki.com.cn/Article/CJFDTOTAL-RMJZ202002015.htm [6] 孙岩, 邹月芬, 郝跃峰, 等. 磁共振BLADE序列与小FOV表面线圈在距骨软骨成像中的应用[J]. 临床放射学杂志, 2020, 39(3): 560-5. https://www.cnki.com.cn/Article/CJFDTOTAL-LCFS202003031.htm [7] Xu Y, He L, Han Y, et al. Evaluation of 3-dimensional magnetic resonance imaging (3D MRI) in diagnosing anterior talofibular ligament injury[J]. Med Sci Monit, 2021, 27: e927920. [8] 李焕敬, 张大光, 刘振旺, 等. 军事训练致踝关节损伤91例MRI表现[J]. 实用医药杂志, 2020, 37(10): 927-9. https://www.cnki.com.cn/Article/CJFDTOTAL-QEYY202010022.htm [9] 黄莹, 刘旭红, 张乾营, 等. 一种用于磁共振检查的踝关节加压器设计与应用[J]. 中国医学装备, 2021, 18(7): 189-92. doi: 10.3969/J.ISSN.1672-8270.2021.07.043 [10] 陈地友, 冉启胜. 四通道相控阵表面线圈与十二通道头颅正交线圈在踝关节MRI中的应用比较[J]. 中国医疗设备, 2021, 36(7): 77-80. doi: 10.3969/j.issn.1674-1633.2021.07.017 [11] Yao WZ, Zhang YJ, Zhang L, et al. MRI features of and factors related to ankle injuries in asymptomatic amateur marathon runners[J]. Skeletal Radiol, 2021, 50(1): 87-95. doi: 10.1007/s00256-020-03530-9 [12] Yan W, Meng XH, Sun JL, et al. Intelligent localization and quantitative evaluation of anterior talofibular ligament injury using magnetic resonance imaging of ankle[J]. BMC Med Imaging, 2021, 21(1): 130. doi: 10.1186/s12880-021-00660-x [13] Borderud SP, Li Y, Burkhalter JE, et al. Electronic cigarette use among patients with cancer: characteristics of electronic cigarette users and their smoking cessation outcomes[J]. Cancer, 2014, 120 (22): 3527-35. doi: 10.1002/cncr.28811 [14] 朱乐发, 肖叶玉, 夏学文, 等. 不同翻转角双回波稳态序列MRI评价膝关节骨性关节炎软骨损伤[J]. 中国医学影像技术, 2020, 36(11): 1697-701. https://www.cnki.com.cn/Article/CJFDTOTAL-ZYXX202011032.htm [15] 孔龙, 易海, 张刚, 等. 3D-MEDIC-WE序列对骶髂关节炎关节软骨病变的诊断价值[J]. 医学影像学杂志, 2017, 27(8): 1557-60. https://www.cnki.com.cn/Article/CJFDTOTAL-XYXZ201708041.htm [16] Wuennemann F, Kintzelé L, Zeifang F, et al. Diagnostic performance of 3D-multi-Echo-data-image-combination (MEDIC) for evaluating SLAP lesions of the shoulder[J]. BMC Musculoskelet Disord, 2019, 20(1): 598. doi: 10.1186/s12891-019-2986-1 [17] Baur OL, Den Harder JM, Hemke R, et al. The Road to optimal acceleration of Dixon imaging and quantitative T2-mapping in the ankle using compressed sensing and parallel imaging[J]. Eur J Radiol, 2020, 132: 109295. doi: 10.1016/j.ejrad.2020.109295 [18] 李萌菲, 胡斌, 王国华. 定量MRI技术在关节软骨修复评估中的研究进展[J]. 临床放射学杂志, 2020, 39(9): 1894-6. https://www.cnki.com.cn/Article/CJFDTOTAL-LCFS202009050.htm [19] 陈逸群, 赵雪文. 3.0T MRI3D-VIBE序列联合OsiriX软件半自动分割在膝骨关节炎软骨体积测量中的应用价值[J]. 影像技术, 2022, 34 (1): 22-6. https://www.cnki.com.cn/Article/CJFDTOTAL-YIXI202201004.htm [20] Subramanian A, Hegde G, Azzopardi C, et al. TI VIBE inversion MRI-An alternative to CT for imaging of hip pain[J]. J Clin Orthop Trauma, 2021, 19: 196-9. doi: 10.1016/j.jcot.2021.05.030