A new development in the application of resting functional magnetic resonance in temporal lobe epilepsy
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摘要: 颞叶癫痫是成人最常见的局灶性癫痫。目前诊断癫痫的方法仍然以症状、电生理居多，脑电图检查中，发作期间的癫痫样放电是诊断癫痫的重要依据，但患者发作期较为短暂，捕捉异常脑电波信号具有一定困难，因此某种程度上，需要借助MRI进一步诊断。但仅依靠普通MRI检查在识别这些患者的癫痫发生区方面仍存在固有的困难。然而，借助改进的定位技术，颞叶癫痫通常可以正确识别。近年来，对于颞叶癫痫的研究已经转移到“功能”磁共振上。在“静止状态”下与大脑打交道。本文对目前可以分析颞叶癫痫患者静止状态的fMRI数据的诸多方法进行概述，包括低频振幅、基于种子的功能连接分析、区域同质性分析、独立成分分析、图分析等。Abstract: Temporal lobe epilepsy (TLE) is the most common focal epilepsy in adults. There are still inherent difficulties in identifying epileptic regions in these patients only by relying on ordinary MRI. However, with improved localization techniques, TLE can often be correctly identified. In recent years, the study of TLE has shifted to "functional" MRI. Working with the brain in a "static state". There are many ways to analyze fMRI data from the quiescent state of patients with TLE, and we will provide an extensive overview of them in this review.
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图 1 大脑的轴结构图
低频波动幅度的结果（静止状态功能磁共振成像）; 暖色表示TLE>NC, 冷色表示NC>TLE.
Figure 1. Axial map of the brain.
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