Effect of straight cervical curvature on early cervical disc degeneration in college students by magnetic resonance T2-mapping
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摘要:
目的应用磁共振T2-mapping成像技术研究颈椎曲度变直对某高校大学生颈椎间盘早期退变的影响。 方法招募56名汕头地区在校大学生行颈椎X线侧位和颈椎磁共振T2-mapping成像检查，根据颈椎曲度弧弦距将其分为颈曲变直组（n=43）和颈曲正常组（n=13），分析颈椎曲度弧弦距与颈椎间盘髓核T2值的相关性，并比较两组间对应节段颈椎间盘髓核T2值的差异。 结果该校大学生颈椎间盘髓核的T2值与颈椎曲度弧弦距呈正相关（r=0.277，P < 0.05）；颈曲变直组与颈曲正常组仅在C2/3、C3/4节段颈椎间盘髓核T2值的差异有统计学意义（P < 0.05），其它节段差异无统计学意义（P > 0.05）。 结论颈椎曲度变直可能是加速大学生颈椎间盘髓核退变的因素之一，磁共振T2-mapping成像技术能检测颈椎间盘髓核退变早期的生化成分的变化，这将为颈椎间盘退变的预防和早期干预提供依据。 -
关键词:
- 颈椎曲度 /
- 椎间盘退变 /
- 磁共振成像 /
- T2-mapping成像
Abstract:ObjectiveTo explore the effect of straight cervical curvature on early cervical disc degeneration in college students using magnetic resonance T2-mapping. MethodsFifty-six college students in Shantou area were recruited for lateral X-ray and T2-mapping. They were divided into straight cervical curvature group (n=43) and normal cervical curvature group (n=13) according to arc string distance of cervical spine. Spearman correlation was used for analyzing the correlation between the arc string distance of cervical curvature and T2 values of cervical disc nucleus pulposus. The T2 values between the two groups were compared using Wilcoxon's rank sum test. ResultsPositive correlation was observed between T2 value of the cervical disc nucleus pulposus and the arc string distance of cervical curvature (r=0.277, P < 0.05). The results showed that the differences of the T2 value of cervical nucleus pulposus in C2/3 and C3/4 segments between straight cervical curvature group and normal cervical curvature group were significant (P < 0.05), with no significant different in other segments (P > 0.05). ConclusionStraight cervical curvature may be one of the factors, which can accelerate the degeneration of cervical disc nucleus pulposus in college students. T2-mapping can detect changes of biochemical components in the early cervical disc degeneration, which will provide basis for the prevention and early intervention of cervical disc degeneration. -
图 2 颈曲变直的X线侧位片
Figure 2. The lateral cervical plain film of straight cervical curvature
图 3 颈椎间盘测量T2值的ROI设置（红色椭圆形）示意图
Figure 3. Diagrammatic sketch of the method of ROI (red oval) setting for T2 values measurement
表 1 颈曲变直组与颈曲正常组C2~7相应各节段髓核T2值的比较[M (P25, P75), ms]
Table 1. Comparison of T2 values of C2-7 corresponding segments of nucleus pulposus between straight and normal cervical curvature group
椎间盘节段 C2/3 C3/4 C4/5 C5/6 C6/7 颈曲变直组（n=43） 65.037 63.798 65.809 72.213 92.000 (57.556, 76.676) (56.280, 71.553) (58.116, 74.054) (58.967, 79.612) (73.868, 110.090) 颈曲正常组（n=13） 75.573 72.044 65.163 66.568 111.550 (67.003, 93.978) (59.982, 86.504) (61.778, 74.057) (65.095, 85.883) (86.943, 118.115) Z -2.319 -2.067 -0.049 -0.553 -1.659 P 0.020 0.039 0.961 0.580 0.097 
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