Advances of indocyanine green fluorescence imaging in diagnosis and treatment of hepatobiliary and pancreatic surgery diseases
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摘要: 近年来, 吲哚菁绿分子荧光影像技术在肝胆胰外科中的应用日益广泛, 该技术应用日趋成熟, 在肝胆胰外科围手术期中扮演着重要角色。吲哚菁绿在肝脏外科中的应用主要包括术前评估和术中进行微小癌灶的侦测、肿瘤边界界定和左右半肝界定, 可使肝切除手术更为精准、安全, 尤其是在肿瘤切除术中可以有效减低手术风险并提高R0切除率; 在胆道外科中对肝内胆管癌、胆囊切除和胰腺肿瘤的应用较为广泛, 可避免胆道的损伤和提高胰腺肿瘤的诊治效果。故本文通过查阅近几年国内外关于吲哚菁绿在肝胆胰外科应用的研究成果, 如在肝切除术前评估肝脏功能, 在肝切除术中用于侦测肝断面边缘残余肿瘤及术中微小癌灶, 以及在肝肿瘤边界、左右半肝界定、腹腔镜胆囊切除术、肝内胆管癌、胰腺外科等中的应用, 标题全方位地阐述吲哚菁绿分子荧光影像技术在肝胆胰外科疾病中的相关应用。Abstract: In recent years, the application of indocyanine green molecular fluorescence imaging in hepato-biliary and pancreatic surgery is more extensive. The application of indocyanine green molecular fluorescence imaging is more and more mature. It plays an indispensable role in the perioperative period of hepato-biliary and pancreatic surgery. The application of indocyanine green in liver surgery mainly includes preoperative evaluation and intraoperative detection of small cancer foci, tumor boundary definition and left and right hemiliver definition, which can make liver resection more accurate and safe, especially in tumor resection can effectively reduce the risk of surgery and improve the R0 resection rate. It is widely used in biliary surgery for intrahepatic cholangiocarcinoma, cholecystectomy and pancreatic tumor, which can avoid the injury of biliary tract and improve the diagnosis and treatment effect of pancreatic tumor. Therefore, by referring to the recent domestic and foreign research results on the application of indocyanine green in hepato-biliary and pancreatic surgery, this paper comprehensively expounds the application of ICG molecular fluorescence imaging technology in hepato-biliary and pancreatic surgery.
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Key words:
- indocyanine green /
- liver volume /
- microcarcinoma /
- liver tumor boundary /
- hepatectomy
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