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胃癌相关LncRNA Gas5/miRNA信号通路的研究进展

肖杨 张金辉 方法

肖杨, 张金辉, 方法. 胃癌相关LncRNA Gas5/miRNA信号通路的研究进展[J]. 分子影像学杂志, 2019, 42(2): 217-221. doi: 10.12122/j.issn.1674-4500.2019.02.18
引用本文: 肖杨, 张金辉, 方法. 胃癌相关LncRNA Gas5/miRNA信号通路的研究进展[J]. 分子影像学杂志, 2019, 42(2): 217-221. doi: 10.12122/j.issn.1674-4500.2019.02.18
Yang XIAO, Jinhui ZHANG, Fa FANG. Research progress of gastric cancer related LncRNA Gas5/miRNA signaling pathway[J]. Journal of Molecular Imaging, 2019, 42(2): 217-221. doi: 10.12122/j.issn.1674-4500.2019.02.18
Citation: Yang XIAO, Jinhui ZHANG, Fa FANG. Research progress of gastric cancer related LncRNA Gas5/miRNA signaling pathway[J]. Journal of Molecular Imaging, 2019, 42(2): 217-221. doi: 10.12122/j.issn.1674-4500.2019.02.18

胃癌相关LncRNA Gas5/miRNA信号通路的研究进展

doi: 10.12122/j.issn.1674-4500.2019.02.18
详细信息
    作者简介:

    肖杨,在读硕士研究生,E-mail:1458585655@qq.com

    通讯作者:

    张金辉,主任医师,博士生导师,E-mail:zhangjinhui2001@126.com

Research progress of gastric cancer related LncRNA Gas5/miRNA signaling pathway

  • 摘要: 胃癌是消化系统中好发的恶性肿瘤之一。近年来,随着临床诊疗技术的提高,胃癌的5年生存率有了显著上升趋势,而进展期胃癌预后仍不理想。明确胃癌发病的分子机制与寻找新的分子靶点成为胃癌治疗中的关键。本文归纳了近年来国内外学者对长链非编码RNA Gas5在胃癌患者中通过调控相关miRNA表达影响胃癌发生发展的研究,指出LncRNA Gas5在胃癌中的表达机制,及其对相关miRNA影响的主要研究进展,并就该分子机制在胃癌生长、增殖、转移、预后等过程中起到的临床诊疗意义进行探讨。

     

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出版历程
  • 收稿日期:  2019-01-11
  • 刊出日期:  2019-04-01

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